Cytomorphological and Cytomorphometric Analysis of Oral Squames in Smokers Using Computer Aided Image Analysis System
ABSTRACT Objective: This study aimed to assess the impact of smoking on oral mucosa and evaluate the role of cytomorphometry in diagnosing and prognosing potentially malignant disorders. Study Design: The study included 75 patients both smokers and non-smokers with and without smoking-related lesion...
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| Veröffentlicht in: | Journal of pharmacy & bioallied science 2024-12, Vol.16 (Suppl 4), p.S3524-S3527 |
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| container_issue | Suppl 4 |
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| container_title | Journal of pharmacy & bioallied science |
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| creator | Choudhary, Priyanka Kasana, Jyoti Bhati, Bhupender Chandavarkar, Vidyadevi Bhargava, Deepak Mishra, Mithilesh N |
| description | ABSTRACT Objective: This study aimed to assess the impact of smoking on oral mucosa and evaluate the role of cytomorphometry in diagnosing and prognosing potentially malignant disorders. Study Design: The study included 75 patients both smokers and non-smokers with and without smoking-related lesions. We measured cellular diameter (CD), nuclear diameter (ND), cellular area (CA) and nuclear area (NA) of buccal mucosa squames using PAP stain and image analysis software (Pixel Pro by Labo Med). Results: Smokers, regardless of lesion presence showed increased ND, decreased CD, increased NA and decreased CA compared to non-smokers. ANOVA and t-tests indicated significant differences (P < 0.001). Conclusion: Exfoliative cytology proves to be a simple, fast and cost-effective method for screening potentially malignant disorders of the oral cavity. Keywords: Computer-aided image analysis, cytomorphology, cytomorphometry, oral squames, smoking |
| doi_str_mv | 10.4103/jpbs.jpbs_1061_24 |
| format | Article |
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Study Design: The study included 75 patients both smokers and non-smokers with and without smoking-related lesions. We measured cellular diameter (CD), nuclear diameter (ND), cellular area (CA) and nuclear area (NA) of buccal mucosa squames using PAP stain and image analysis software (Pixel Pro by Labo Med). Results: Smokers, regardless of lesion presence showed increased ND, decreased CD, increased NA and decreased CA compared to non-smokers. ANOVA and t-tests indicated significant differences (P < 0.001). Conclusion: Exfoliative cytology proves to be a simple, fast and cost-effective method for screening potentially malignant disorders of the oral cavity. Keywords: Computer-aided image analysis, cytomorphology, cytomorphometry, oral squames, smoking</description><identifier>ISSN: 0976-4879</identifier><identifier>EISSN: 0975-7406</identifier><identifier>DOI: 10.4103/jpbs.jpbs_1061_24</identifier><language>eng</language><publisher>Mumbai: Medknow Publications and Media Pvt. Ltd</publisher><subject>Buccal mucosa ; computer-aided image analysis ; Cytology ; cytomorphology ; cytomorphometry ; Image processing ; Medical research ; Medicine, Experimental ; Oral cavity ; oral squames ; Patient compliance ; Smokers ; Smoking</subject><ispartof>Journal of pharmacy & bioallied science, 2024-12, Vol.16 (Suppl 4), p.S3524-S3527</ispartof><rights>COPYRIGHT 2024 Medknow Publications and Media Pvt. Ltd.</rights><rights>2024. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c2464-ccaea0f720805fdb85ef12fe50deea829c483f7fdffb60b101bfc45f05cfec143</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,860,2095,27903,27904</link.rule.ids></links><search><creatorcontrib>Choudhary, Priyanka</creatorcontrib><creatorcontrib>Kasana, Jyoti</creatorcontrib><creatorcontrib>Bhati, Bhupender</creatorcontrib><creatorcontrib>Chandavarkar, Vidyadevi</creatorcontrib><creatorcontrib>Bhargava, Deepak</creatorcontrib><creatorcontrib>Mishra, Mithilesh N</creatorcontrib><title>Cytomorphological and Cytomorphometric Analysis of Oral Squames in Smokers Using Computer Aided Image Analysis System</title><title>Journal of pharmacy & bioallied science</title><description>ABSTRACT Objective: This study aimed to assess the impact of smoking on oral mucosa and evaluate the role of cytomorphometry in diagnosing and prognosing potentially malignant disorders. Study Design: The study included 75 patients both smokers and non-smokers with and without smoking-related lesions. We measured cellular diameter (CD), nuclear diameter (ND), cellular area (CA) and nuclear area (NA) of buccal mucosa squames using PAP stain and image analysis software (Pixel Pro by Labo Med). Results: Smokers, regardless of lesion presence showed increased ND, decreased CD, increased NA and decreased CA compared to non-smokers. ANOVA and t-tests indicated significant differences (P < 0.001). Conclusion: Exfoliative cytology proves to be a simple, fast and cost-effective method for screening potentially malignant disorders of the oral cavity. Keywords: Computer-aided image analysis, cytomorphology, cytomorphometry, oral squames, smoking</description><subject>Buccal mucosa</subject><subject>computer-aided image analysis</subject><subject>Cytology</subject><subject>cytomorphology</subject><subject>cytomorphometry</subject><subject>Image processing</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Oral cavity</subject><subject>oral squames</subject><subject>Patient compliance</subject><subject>Smokers</subject><subject>Smoking</subject><issn>0976-4879</issn><issn>0975-7406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNptUk2L2zAQNaWFLtv9Ab0JenaqT38cQ-hHYGEP6Z6FPBq5Si3LK9mH_Ps6ydK00BmYGR7vPRhmiuIjoxvJqPh8nLq8ORfNaMU0l2-KO9rWqqwlrd5e5qqUTd2-Lx5yPtI1RMtbJu6KZXeaY4hp-hmH2HswAzGjJTc04Jw8kO1ohlP2mURHntLKOrwsJmAmfiSHEH9hyuQ5-7EnuximZcZEtt6iJftgerzJD6c8Y_hQvHNmyPjw2u-L569ffuy-l49P3_a77WMJXFayBDBoqKs5bahytmsUOsYdKmoRTcNbkI1wtbPOdRXtGGWdA6kcVeAQmBT3xf7qa6M56in5YNJJR-P1BYip1ybNHgbUvKtp1dqKUVASHG9FpTqqFFCooONnr09XrynFlwXzrI9xSeteWQsmW8GE4uzG6s1q6kcX52Qg-Ax623C2nqthZ9bmP6w1LQYPcUTnV_wfAbsKIMWcE7o_yzCqzz-gL-f_-wfEbw2fp38</recordid><startdate>20241201</startdate><enddate>20241201</enddate><creator>Choudhary, Priyanka</creator><creator>Kasana, Jyoti</creator><creator>Bhati, Bhupender</creator><creator>Chandavarkar, Vidyadevi</creator><creator>Bhargava, Deepak</creator><creator>Mishra, Mithilesh N</creator><general>Medknow Publications and Media Pvt. Ltd</general><general>Medknow Publications & Media Pvt. 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Study Design: The study included 75 patients both smokers and non-smokers with and without smoking-related lesions. We measured cellular diameter (CD), nuclear diameter (ND), cellular area (CA) and nuclear area (NA) of buccal mucosa squames using PAP stain and image analysis software (Pixel Pro by Labo Med). Results: Smokers, regardless of lesion presence showed increased ND, decreased CD, increased NA and decreased CA compared to non-smokers. ANOVA and t-tests indicated significant differences (P < 0.001). Conclusion: Exfoliative cytology proves to be a simple, fast and cost-effective method for screening potentially malignant disorders of the oral cavity. Keywords: Computer-aided image analysis, cytomorphology, cytomorphometry, oral squames, smoking</abstract><cop>Mumbai</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><doi>10.4103/jpbs.jpbs_1061_24</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Buccal mucosa computer-aided image analysis Cytology cytomorphology cytomorphometry Image processing Medical research Medicine, Experimental Oral cavity oral squames Patient compliance Smokers Smoking |
| title | Cytomorphological and Cytomorphometric Analysis of Oral Squames in Smokers Using Computer Aided Image Analysis System |
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