The Correlation between NPS and Polysubstance Use in High-Risk Population: a Five-year Longitudinal Study in Taiwan
The emergence of new synthetic substances (NPS) leads to rapid changes in substance prevalence. Here urine analysis and questionnaires were employed to construct a landscape of substance abuse. 3,064 urine samples were randomly selected from suspected substance abusers (N = 6,335) from 2014 to 2018...
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Veröffentlicht in: | International journal of mental health and addiction 2024-12, Vol.22 (6), p.3859-3877 |
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creator | Yang, Da-Peng Ting, Te-Tien Kuo, Yun-Ning Chen, Wei-Ru Liu, Hsin-Tung Chiu, Jui-Yi Jair, Yung-Cheng Chen, Jung-Hsuan Lin, Mei-Chih Hsu, Ya-Hui Chen, Huei-Wen Chen, Pai-Shan |
description | The emergence of new synthetic substances (NPS) leads to rapid changes in substance prevalence. Here urine analysis and questionnaires were employed to construct a landscape of substance abuse. 3,064 urine samples were randomly selected from suspected substance abusers (N = 6,335) from 2014 to 2018 in Taiwan. Demographic information was self-reported. Principal component analysis (PCA) were used to explore the substance pattern. The positive detection of NPS reached 19.6%. The highest links of polysubstance use were the use of phenethylamines with the co-use of amphetamines (aOR = 4.33), benzodiazepines (aOR = 2.09), and synthetic cathinones (aOR = 5.01) and the use of synthetic cathinones with the co-use of ketamine (aOR = 6.72) and benzodiazepines (aOR = 2.62). No evidence indicating an increase in the use of NPS/other substances as a replacement for traditional substances. The presence of polysubstance patterns may be due to similarities in the effects of the various substances or users undergoing a transition in their substance abuse patterns. |
doi_str_mv | 10.1007/s11469-023-01088-w |
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Here urine analysis and questionnaires were employed to construct a landscape of substance abuse. 3,064 urine samples were randomly selected from suspected substance abusers (N = 6,335) from 2014 to 2018 in Taiwan. Demographic information was self-reported. Principal component analysis (PCA) were used to explore the substance pattern. The positive detection of NPS reached 19.6%. The highest links of polysubstance use were the use of phenethylamines with the co-use of amphetamines (aOR = 4.33), benzodiazepines (aOR = 2.09), and synthetic cathinones (aOR = 5.01) and the use of synthetic cathinones with the co-use of ketamine (aOR = 6.72) and benzodiazepines (aOR = 2.62). No evidence indicating an increase in the use of NPS/other substances as a replacement for traditional substances. 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Here urine analysis and questionnaires were employed to construct a landscape of substance abuse. 3,064 urine samples were randomly selected from suspected substance abusers (N = 6,335) from 2014 to 2018 in Taiwan. Demographic information was self-reported. Principal component analysis (PCA) were used to explore the substance pattern. The positive detection of NPS reached 19.6%. The highest links of polysubstance use were the use of phenethylamines with the co-use of amphetamines (aOR = 4.33), benzodiazepines (aOR = 2.09), and synthetic cathinones (aOR = 5.01) and the use of synthetic cathinones with the co-use of ketamine (aOR = 6.72) and benzodiazepines (aOR = 2.62). No evidence indicating an increase in the use of NPS/other substances as a replacement for traditional substances. 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Ting, Te-Tien ; Kuo, Yun-Ning ; Chen, Wei-Ru ; Liu, Hsin-Tung ; Chiu, Jui-Yi ; Jair, Yung-Cheng ; Chen, Jung-Hsuan ; Lin, Mei-Chih ; Hsu, Ya-Hui ; Chen, Huei-Wen ; Chen, Pai-Shan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c319t-6af387ba24093dcb2edab02793315dddfd63249757d91066f06f5eb69a3a6e933</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Amphetamines</topic><topic>Cocaine</topic><topic>Community and Environmental Psychology</topic><topic>Criminal investigations</topic><topic>Drug abuse</topic><topic>Drug use</topic><topic>Ecstasy</topic><topic>Health Psychology</topic><topic>Ketamine</topic><topic>Law enforcement</topic><topic>Marijuana</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Methadone</topic><topic>Narcotics</topic><topic>Original Article</topic><topic>Population</topic><topic>Psychiatry</topic><topic>Psychology</topic><topic>Public Health</topic><topic>Questionnaires</topic><topic>Regression analysis</topic><topic>Rehabilitation</topic><topic>Statistical analysis</topic><topic>Urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yang, Da-Peng</creatorcontrib><creatorcontrib>Ting, Te-Tien</creatorcontrib><creatorcontrib>Kuo, Yun-Ning</creatorcontrib><creatorcontrib>Chen, Wei-Ru</creatorcontrib><creatorcontrib>Liu, Hsin-Tung</creatorcontrib><creatorcontrib>Chiu, Jui-Yi</creatorcontrib><creatorcontrib>Jair, Yung-Cheng</creatorcontrib><creatorcontrib>Chen, Jung-Hsuan</creatorcontrib><creatorcontrib>Lin, Mei-Chih</creatorcontrib><creatorcontrib>Hsu, Ya-Hui</creatorcontrib><creatorcontrib>Chen, Huei-Wen</creatorcontrib><creatorcontrib>Chen, Pai-Shan</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>International journal of mental health and addiction</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yang, Da-Peng</au><au>Ting, Te-Tien</au><au>Kuo, Yun-Ning</au><au>Chen, Wei-Ru</au><au>Liu, Hsin-Tung</au><au>Chiu, Jui-Yi</au><au>Jair, Yung-Cheng</au><au>Chen, Jung-Hsuan</au><au>Lin, Mei-Chih</au><au>Hsu, Ya-Hui</au><au>Chen, Huei-Wen</au><au>Chen, Pai-Shan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Correlation between NPS and Polysubstance Use in High-Risk Population: a Five-year Longitudinal Study in Taiwan</atitle><jtitle>International journal of mental health and addiction</jtitle><stitle>Int J Ment Health Addiction</stitle><date>2024-12-01</date><risdate>2024</risdate><volume>22</volume><issue>6</issue><spage>3859</spage><epage>3877</epage><pages>3859-3877</pages><issn>1557-1874</issn><eissn>1557-1882</eissn><abstract>The emergence of new synthetic substances (NPS) leads to rapid changes in substance prevalence. Here urine analysis and questionnaires were employed to construct a landscape of substance abuse. 3,064 urine samples were randomly selected from suspected substance abusers (N = 6,335) from 2014 to 2018 in Taiwan. Demographic information was self-reported. Principal component analysis (PCA) were used to explore the substance pattern. The positive detection of NPS reached 19.6%. The highest links of polysubstance use were the use of phenethylamines with the co-use of amphetamines (aOR = 4.33), benzodiazepines (aOR = 2.09), and synthetic cathinones (aOR = 5.01) and the use of synthetic cathinones with the co-use of ketamine (aOR = 6.72) and benzodiazepines (aOR = 2.62). No evidence indicating an increase in the use of NPS/other substances as a replacement for traditional substances. 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subjects | Amphetamines Cocaine Community and Environmental Psychology Criminal investigations Drug abuse Drug use Ecstasy Health Psychology Ketamine Law enforcement Marijuana Medicine Medicine & Public Health Methadone Narcotics Original Article Population Psychiatry Psychology Public Health Questionnaires Regression analysis Rehabilitation Statistical analysis Urine |
title | The Correlation between NPS and Polysubstance Use in High-Risk Population: a Five-year Longitudinal Study in Taiwan |
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