Biochemical, histological, and molecular investigation of fish exposed to a brewery effluent
Background Breweries' industrial processes produce much effluent, which, if improperly managed, could contaminate the aquatic bodies that receive them. The effect of brewery effluent on fish health was investigated to assess the extent of pollution on the fish population. Samples of Clarias gar...
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| Veröffentlicht in: | Journal of basic & applied zoology 2024-12, Vol.85 (1), p.64-12 |
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| creator | Olorunfemi, Daniel I. Nkemneme, Gabriela-Mary O. Afolabi, Olumide Ebisintei, Precious Okunoja, Happiness B. Orororo, Osuvwe C. Kpomah, Enyohwo D. Tesi, Juliet N. |
| description | Background
Breweries' industrial processes produce much effluent, which, if improperly managed, could contaminate the aquatic bodies that receive them. The effect of brewery effluent on fish health was investigated to assess the extent of pollution on the fish population. Samples of
Clarias gariepinus
L were exposed to varying concentrations of brewery effluent. After exposure, key biochemical indicators of oxidative stress response were analyzed. Messenger RNA expressions of genes associated with growth, reproduction, oxidative stress, and toxicity were quantified. The histopathological architecture of the liver was also examined.
Results
Exposure of fish to the brewery effluent increased conjugated diene and malondialdehyde levels, while the activity of antioxidant enzymes (catalase and SOD) significantly (
p
|
| doi_str_mv | 10.1186/s41936-024-00418-1 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_proquest_journals_3147793534</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_ba9f0c9a77e94515aa843aa7a085a451</doaj_id><sourcerecordid>3147793534</sourcerecordid><originalsourceid>FETCH-LOGICAL-d1381-ef08ef9333cbb00109d830d7a8ec752e6c4a8dd8f8812b34fec37f16035eaa803</originalsourceid><addsrcrecordid>eNpFkU1rHDEMhodAoSHNH8jJ0GumlcaeGfuYhn4EArmk0EPAaDzyrpfZ8daebZJ_HzcTiC5C4tUriaeqLhC-IOrua1ZoZFdDo2oAhbrGk-q0AQO1MfDnY3We8w5KGIVNh6fVw7cQ3Zb3wdF0KbYhL3GKm7WieRT7OLE7TpREmP9xXsKGlhBnEb3wIW8FPx1i5lEsUZAYEj9yehbs_XTkeflUffA0ZT5_y2fV7x_f769_1bd3P2-ur27rEaXGmj1o9kZK6YYBAMGMWsLYk2bXtw13TpEeR-21xmaQyrOTvccOZMtEGuRZdbP6jpF29pDCntKzjRTsayOmjaW0BDexHch4cIb6no1qsS3zShL1BLql0ihen1evQ4p_j-Vju4vHNJfzrUTV90a2UhWVXFW5bJs3nN5VCPY_CbuSsIWEfSVhUb4A-iR96A</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3147793534</pqid></control><display><type>article</type><title>Biochemical, histological, and molecular investigation of fish exposed to a brewery effluent</title><source>DOAJ Directory of Open Access Journals</source><source>Springer Nature OA Free Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Olorunfemi, Daniel I. ; Nkemneme, Gabriela-Mary O. ; Afolabi, Olumide ; Ebisintei, Precious ; Okunoja, Happiness B. ; Orororo, Osuvwe C. ; Kpomah, Enyohwo D. ; Tesi, Juliet N.</creator><creatorcontrib>Olorunfemi, Daniel I. ; Nkemneme, Gabriela-Mary O. ; Afolabi, Olumide ; Ebisintei, Precious ; Okunoja, Happiness B. ; Orororo, Osuvwe C. ; Kpomah, Enyohwo D. ; Tesi, Juliet N.</creatorcontrib><description>Background
Breweries' industrial processes produce much effluent, which, if improperly managed, could contaminate the aquatic bodies that receive them. The effect of brewery effluent on fish health was investigated to assess the extent of pollution on the fish population. Samples of
Clarias gariepinus
L were exposed to varying concentrations of brewery effluent. After exposure, key biochemical indicators of oxidative stress response were analyzed. Messenger RNA expressions of genes associated with growth, reproduction, oxidative stress, and toxicity were quantified. The histopathological architecture of the liver was also examined.
Results
Exposure of fish to the brewery effluent increased conjugated diene and malondialdehyde levels, while the activity of antioxidant enzymes (catalase and SOD) significantly (
p
< 0.05) decreased relative to control fish. The effluent increased the mRNA expression of growth hormones (GHs), CAMKIIg, MEL1C, IL-1β, CYP11A, HSP70, and DMRT1, while decreasing the expression of HSD17B and FOXL2 when compared to control fish (
p
< 0.05). The histological study revealed liver degeneration from the normal architectural structure with simple steatosis and structurally enlarged central vein coupled with Mallory bodies.
Conclusion
The results indicate that effluent discharge from the brewery industry can harm fish population by altering antioxidant enzymes and expression of growth hormones. Hence, prior discharge into water bodies, industrial effluents should be effectively treated to meet standards and guidelines stipulated by environmental regulatory bodies.</description><identifier>EISSN: 2090-990X</identifier><identifier>DOI: 10.1186/s41936-024-00418-1</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Animal Ecology ; Animal Physiology ; Antioxidants ; Aquatic pollution ; Biomedical and Life Sciences ; Breweries ; Brewery factory effluent ; Cell Biology and Genetics ; Effluents ; Embryology ; Entomology ; Enzymes ; Fatty liver ; Gene expression ; Growth hormones ; Hsp70 protein ; Industrial effluents ; Life Sciences ; Oxidative stress ; Parasitology ; Population studies ; Steatosis ; Toxicity ; Water quality ; Zoology</subject><ispartof>Journal of basic & applied zoology, 2024-12, Vol.85 (1), p.64-12</ispartof><rights>The Author(s) 2024</rights><rights>Copyright Springer Nature B.V. Dec 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0002-9217-1530</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1186/s41936-024-00418-1$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://doi.org/10.1186/s41936-024-00418-1$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,864,2102,27924,27925,41120,42189,51576</link.rule.ids></links><search><creatorcontrib>Olorunfemi, Daniel I.</creatorcontrib><creatorcontrib>Nkemneme, Gabriela-Mary O.</creatorcontrib><creatorcontrib>Afolabi, Olumide</creatorcontrib><creatorcontrib>Ebisintei, Precious</creatorcontrib><creatorcontrib>Okunoja, Happiness B.</creatorcontrib><creatorcontrib>Orororo, Osuvwe C.</creatorcontrib><creatorcontrib>Kpomah, Enyohwo D.</creatorcontrib><creatorcontrib>Tesi, Juliet N.</creatorcontrib><title>Biochemical, histological, and molecular investigation of fish exposed to a brewery effluent</title><title>Journal of basic & applied zoology</title><addtitle>JoBAZ</addtitle><description>Background
Breweries' industrial processes produce much effluent, which, if improperly managed, could contaminate the aquatic bodies that receive them. The effect of brewery effluent on fish health was investigated to assess the extent of pollution on the fish population. Samples of
Clarias gariepinus
L were exposed to varying concentrations of brewery effluent. After exposure, key biochemical indicators of oxidative stress response were analyzed. Messenger RNA expressions of genes associated with growth, reproduction, oxidative stress, and toxicity were quantified. The histopathological architecture of the liver was also examined.
Results
Exposure of fish to the brewery effluent increased conjugated diene and malondialdehyde levels, while the activity of antioxidant enzymes (catalase and SOD) significantly (
p
< 0.05) decreased relative to control fish. The effluent increased the mRNA expression of growth hormones (GHs), CAMKIIg, MEL1C, IL-1β, CYP11A, HSP70, and DMRT1, while decreasing the expression of HSD17B and FOXL2 when compared to control fish (
p
< 0.05). The histological study revealed liver degeneration from the normal architectural structure with simple steatosis and structurally enlarged central vein coupled with Mallory bodies.
Conclusion
The results indicate that effluent discharge from the brewery industry can harm fish population by altering antioxidant enzymes and expression of growth hormones. Hence, prior discharge into water bodies, industrial effluents should be effectively treated to meet standards and guidelines stipulated by environmental regulatory bodies.</description><subject>Animal Ecology</subject><subject>Animal Physiology</subject><subject>Antioxidants</subject><subject>Aquatic pollution</subject><subject>Biomedical and Life Sciences</subject><subject>Breweries</subject><subject>Brewery factory effluent</subject><subject>Cell Biology and Genetics</subject><subject>Effluents</subject><subject>Embryology</subject><subject>Entomology</subject><subject>Enzymes</subject><subject>Fatty liver</subject><subject>Gene expression</subject><subject>Growth hormones</subject><subject>Hsp70 protein</subject><subject>Industrial effluents</subject><subject>Life Sciences</subject><subject>Oxidative stress</subject><subject>Parasitology</subject><subject>Population studies</subject><subject>Steatosis</subject><subject>Toxicity</subject><subject>Water quality</subject><subject>Zoology</subject><issn>2090-990X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>DOA</sourceid><recordid>eNpFkU1rHDEMhodAoSHNH8jJ0GumlcaeGfuYhn4EArmk0EPAaDzyrpfZ8daebZJ_HzcTiC5C4tUriaeqLhC-IOrua1ZoZFdDo2oAhbrGk-q0AQO1MfDnY3We8w5KGIVNh6fVw7cQ3Zb3wdF0KbYhL3GKm7WieRT7OLE7TpREmP9xXsKGlhBnEb3wIW8FPx1i5lEsUZAYEj9yehbs_XTkeflUffA0ZT5_y2fV7x_f769_1bd3P2-ur27rEaXGmj1o9kZK6YYBAMGMWsLYk2bXtw13TpEeR-21xmaQyrOTvccOZMtEGuRZdbP6jpF29pDCntKzjRTsayOmjaW0BDexHch4cIb6no1qsS3zShL1BLql0ihen1evQ4p_j-Vju4vHNJfzrUTV90a2UhWVXFW5bJs3nN5VCPY_CbuSsIWEfSVhUb4A-iR96A</recordid><startdate>20241201</startdate><enddate>20241201</enddate><creator>Olorunfemi, Daniel I.</creator><creator>Nkemneme, Gabriela-Mary O.</creator><creator>Afolabi, Olumide</creator><creator>Ebisintei, Precious</creator><creator>Okunoja, Happiness B.</creator><creator>Orororo, Osuvwe C.</creator><creator>Kpomah, Enyohwo D.</creator><creator>Tesi, Juliet N.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><general>SpringerOpen</general><scope>C6C</scope><scope>7SS</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-9217-1530</orcidid></search><sort><creationdate>20241201</creationdate><title>Biochemical, histological, and molecular investigation of fish exposed to a brewery effluent</title><author>Olorunfemi, Daniel I. ; Nkemneme, Gabriela-Mary O. ; Afolabi, Olumide ; Ebisintei, Precious ; Okunoja, Happiness B. ; Orororo, Osuvwe C. ; Kpomah, Enyohwo D. ; Tesi, Juliet N.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-d1381-ef08ef9333cbb00109d830d7a8ec752e6c4a8dd8f8812b34fec37f16035eaa803</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Animal Ecology</topic><topic>Animal Physiology</topic><topic>Antioxidants</topic><topic>Aquatic pollution</topic><topic>Biomedical and Life Sciences</topic><topic>Breweries</topic><topic>Brewery factory effluent</topic><topic>Cell Biology and Genetics</topic><topic>Effluents</topic><topic>Embryology</topic><topic>Entomology</topic><topic>Enzymes</topic><topic>Fatty liver</topic><topic>Gene expression</topic><topic>Growth hormones</topic><topic>Hsp70 protein</topic><topic>Industrial effluents</topic><topic>Life Sciences</topic><topic>Oxidative stress</topic><topic>Parasitology</topic><topic>Population studies</topic><topic>Steatosis</topic><topic>Toxicity</topic><topic>Water quality</topic><topic>Zoology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Olorunfemi, Daniel I.</creatorcontrib><creatorcontrib>Nkemneme, Gabriela-Mary O.</creatorcontrib><creatorcontrib>Afolabi, Olumide</creatorcontrib><creatorcontrib>Ebisintei, Precious</creatorcontrib><creatorcontrib>Okunoja, Happiness B.</creatorcontrib><creatorcontrib>Orororo, Osuvwe C.</creatorcontrib><creatorcontrib>Kpomah, Enyohwo D.</creatorcontrib><creatorcontrib>Tesi, Juliet N.</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Entomology Abstracts (Full archive)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Journal of basic & applied zoology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Olorunfemi, Daniel I.</au><au>Nkemneme, Gabriela-Mary O.</au><au>Afolabi, Olumide</au><au>Ebisintei, Precious</au><au>Okunoja, Happiness B.</au><au>Orororo, Osuvwe C.</au><au>Kpomah, Enyohwo D.</au><au>Tesi, Juliet N.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Biochemical, histological, and molecular investigation of fish exposed to a brewery effluent</atitle><jtitle>Journal of basic & applied zoology</jtitle><stitle>JoBAZ</stitle><date>2024-12-01</date><risdate>2024</risdate><volume>85</volume><issue>1</issue><spage>64</spage><epage>12</epage><pages>64-12</pages><eissn>2090-990X</eissn><abstract>Background
Breweries' industrial processes produce much effluent, which, if improperly managed, could contaminate the aquatic bodies that receive them. The effect of brewery effluent on fish health was investigated to assess the extent of pollution on the fish population. Samples of
Clarias gariepinus
L were exposed to varying concentrations of brewery effluent. After exposure, key biochemical indicators of oxidative stress response were analyzed. Messenger RNA expressions of genes associated with growth, reproduction, oxidative stress, and toxicity were quantified. The histopathological architecture of the liver was also examined.
Results
Exposure of fish to the brewery effluent increased conjugated diene and malondialdehyde levels, while the activity of antioxidant enzymes (catalase and SOD) significantly (
p
< 0.05) decreased relative to control fish. The effluent increased the mRNA expression of growth hormones (GHs), CAMKIIg, MEL1C, IL-1β, CYP11A, HSP70, and DMRT1, while decreasing the expression of HSD17B and FOXL2 when compared to control fish (
p
< 0.05). The histological study revealed liver degeneration from the normal architectural structure with simple steatosis and structurally enlarged central vein coupled with Mallory bodies.
Conclusion
The results indicate that effluent discharge from the brewery industry can harm fish population by altering antioxidant enzymes and expression of growth hormones. Hence, prior discharge into water bodies, industrial effluents should be effectively treated to meet standards and guidelines stipulated by environmental regulatory bodies.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><doi>10.1186/s41936-024-00418-1</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0002-9217-1530</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Animal Ecology Animal Physiology Antioxidants Aquatic pollution Biomedical and Life Sciences Breweries Brewery factory effluent Cell Biology and Genetics Effluents Embryology Entomology Enzymes Fatty liver Gene expression Growth hormones Hsp70 protein Industrial effluents Life Sciences Oxidative stress Parasitology Population studies Steatosis Toxicity Water quality Zoology |
| title | Biochemical, histological, and molecular investigation of fish exposed to a brewery effluent |
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