Near-IR nanolignin sensitizers based on pyrene-conjugated chlorin and bacteriochlorin for ROS generation, DNA intercalation and bioimaging

Near-infrared (NIR) fluorescent agents are extensively used for biomedical imaging due to their ability for deep tissue penetration. Tetrapyrrole-based photosensitizers are promising candidates in this regard. Further, the extended conjugation of such macromolecules with chromophores can enhance the...

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Veröffentlicht in:	Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2024-12, Vol.13 (1), p.288-34
Hauptverfasser:	Gogde, Kunal, Kirar, Seema, Pujari, Anil Kumar, Mohne, Devesh, Yadav, Ashok Kumar, Bhaumik, Jayeeta
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromophores Conjugation Density Functional Theory Deoxyribonucleic acid DNA DNA - chemistry Fluorescence Fluorescence spectroscopy Humans Infrared imaging Infrared Rays Intercalating Agents - chemical synthesis Intercalating Agents - chemistry Intercalating Agents - pharmacology Intercalation Lignin Medical imaging Molecular Structure Nanoparticles Nanoparticles - chemistry Near infrared radiation Optical Imaging Optical properties pH effects Photodynamic therapy Photosensitizing Agents - chemical synthesis Photosensitizing Agents - chemistry Photosensitizing Agents - pharmacology Porphyrins Porphyrins - chemistry Porphyrins - pharmacology Pyrene Pyrenes - chemistry Reactive oxygen species Reactive Oxygen Species - metabolism Singlet oxygen
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