Dearomative Addition of Carboranyl Anions to Isoquinolinium Salts and Subsequent Reduction to Access Carborane‐Functionalized 1,2‐Dihydroisoquinolines and 1,2,3,4‐Tetrahydroisoquinolines

A dearomative addition of readily available carboranyllithium reagents to isoquinolinium salts gave a series of carborane cage C‐substituted 1,2‐dihydroisoquinolines in 43–85 % yields. Subsequent hydrogenation enabled the facile synthesis of corresponding carboranyl 1,2,3,4‐tetrahydroisoquinolines i...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Asian journal of organic chemistry 2024-12, Vol.13 (12), p.n/a
Hauptverfasser:	Gao, Yun‐Fan, Xu, Chen‐Ming, Yu, Ming‐Hui, Zhang, Yongna, Wu, Xiao‐Jun, Wang, You‐Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	Carborane Carborane-functionalized hydroisoquinolines Carboranes Chemical reduction Dearomative addition Nitrogen heterocycles Reagents Reduction Substitutes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!