EtOH-mediated cascade C(sp 3 )–H alkylation via aromatization-driven [1,6]-hydride transfer: green and divergent synthesis of spirocyclic azepino[4,3,2- cd ]indoles

The development of green and efficient methods for the construction of azepinoindole skeletons remains highly desirable yet challenging. Described herein are the EtOH-mediated cascade C(sp 3 )–H alkylation reactions of 4-dialkylamino-indole-3-carbaldehydes for green and divergent synthesis of spiroc...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Green chemistry : an international journal and green chemistry resource : GC 2024-12, Vol.26 (24), p.11899-11907
Hauptverfasser:	Shen, Yao-Bin, Zhuang, Qian-Hao, Wang, Xiao-Lin, An, Xiao-De, Qiu, Bin, Shi, Tiesheng, Xiao, Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkylation Aromatic compounds Cadmium Cascade chemical reactions Chemical synthesis Divergence Ethanol Hydrides Indoles
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!