Regioselective Intermolecular Hydroamidation of β‐CF3‐1,3‐Enynamides: An Approach to Tri‐Substituted γ‐CF3‐Allenamides

A simple base mediated, highly regioselective 1,4‐hydroamidation of β‐CF3‐1,3‐enynamides with secondary amides for synthesis of tri‐substituted γ‐CF3‐allenamides compounds was developed. N‐alkyl sulfonamides are generally good candidates for the present transformation. γ‐CF3‐allenamides could be emp...

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Veröffentlicht in:	European journal of organic chemistry 2024-11, Vol.27 (44), p.n/a
Hauptverfasser:	Cao, Yuxuan, Yu, Zongxiang, Chen, Yizhen, Liu, Lu, Xiao, Yuanjing
Format:	Artikel
Sprache:	eng
Schlagworte:	1,3-enynamides Allenamides Amides Hydroamidation Regioselectivity Substitutes Sulfonamides Synthesis Ynamides γ-CF3-allenamides
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