On‐Demand Peroxynitrite Overproduction Reprograms Systemic Immune Function for Augmented Sono‐Immunotherapy against Tumor

The undesirable efficacy of immunotherapy in cancer patients is associated with the inactivation of immune responses in tumor immunosuppressive microenvironment (TIME). The pivotal roles of nitric oxide (NO) and peroxynitrite (ONOO−) in immunoregulation can augment anticancer immunotherapy. Here, ul...

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Veröffentlicht in:	Advanced functional materials 2024-11, Vol.34 (48), p.n/a
Hauptverfasser:	Qiu, Luping, Liang, Jing, Xue, Liyun, Qiao, Xiaohui, Xu, Huning, Xiang, Huijing, Chen, Yu, Ding, Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Cell death immune microenvironment programming Immunotherapy Lymphocytes Macrophages nanomedicine Nanoparticles Nitric oxide peroxynitrite generation sono‐immunotherapy Therapy tumor therapy Tumors
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