Excess Androgens in Utero Alters Fetal Testis Development

Prenatal androgenization induces a polycystic ovary syndrome-like phenotype in adult female offspring, which is associated with alterations that can be detected in the fetal ovary, suggesting gestational origins of this condition. We therefore investigated whether increased prenatal androgen exposur...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Endocrinology (Philadelphia) 2013-05, Vol.154 (5), p.1921-1933
Hauptverfasser:	Connolly, Fiona, Rae, Michael T, Bittner, Lilli, Hogg, Kirsten, McNeilly, Alan S, Duncan, W. Colin
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens Androgens - adverse effects Androgens - blood Androgens - pharmacology Animal models Animals Biological and medical sciences Developmental plasticity Diethylstilbestrol Estrogens Exposure Female Fetal Development - drug effects Fetus - drug effects Fetuses Fundamental and applied biological sciences. Psychology Leydig cells Male Males Maternal Exposure - adverse effects Offspring Osmolar Concentration Ovaries Phenotypes Polycystic ovary syndrome Pregnancy Prenatal experience Prenatal Exposure Delayed Effects - blood Prenatal Exposure Delayed Effects - physiopathology Sex Differentiation - drug effects Sheep Testes Testis - drug effects Testis - embryology Testosterone Testosterone propionate Vertebrates: endocrinology Virilism - blood Virilism - embryology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!