Promoter Analysis of Human Corticotropin-Releasing Factor (CRF) Type 1 Receptor and Regulation by CRF and Urocortin

We report the full genomic organization of the human gene for the corticotropin-releasing factor (CRF) receptor type 1 (CRFR1), with complete mapping of exons 1–14. The 5′ flanking region (2.4 kb) of the gene encoding for human CRFR1 was isolated, sequenced, and characterized. Two major transcriptio...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2004-08, Vol.145 (8), p.3971-3983
Hauptverfasser:	Parham, Kelly L, Zervou, Sevasti, Karteris, Emmanouil, Catalano, Rob D, Old, Robert W, Hillhouse, Edward W
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Untranslated Regions - chemistry Adenocarcinoma Amino Acid Sequence Biological and medical sciences Cell activation Corticotropin-releasing hormone Corticotropin-Releasing Hormone - physiology Exons Feedback Feedback loops Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation Gene mapping Humans Kinases Molecular Sequence Data Myometrium Neurotrophin 2 Positive feedback Promoter Regions, Genetic Protein kinase A Protein kinase C Receptors Receptors, Corticotropin-Releasing Hormone - genetics Signal Transduction Teratocarcinoma Transcription, Genetic Tumor cell lines Urocortin Urocortins Vertebrates: endocrinology
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