Steroidogenic Factor-1 Is Essential for Compensatory Adrenal Growth Following Unilateral Adrenalectomy

While the orphan nuclear receptor steroidogenic factor-1 (SF-1) has been shown to function as an induction factor to define adrenocortical cell lineage, it remains unclear whether SF-1 plays an additional role as a growth promoting agent in the adult adrenal cortex. The proliferative potential of th...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2002-08, Vol.143 (8), p.3122-3135
Hauptverfasser:	Beuschlein, Felix, Mutch, Chris, Bavers, David L, Ulrich-Lai, Yvonne M, Engeland, William C, Keegan, Catherine, Hammer, Gary D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal cortex Adrenal glands Adrenalectomy Adrenocorticotropic hormone Agouti-related protein Cell lineage Cell proliferation Proliferating cell nuclear antigen Receptors Serine proteinase
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