Identification of the Lipophilic Factor Produced by Macrophages That Stimulates Steroidogenesis

Abstract Macrophages are known to release a lipophilic factor that stimulates testosterone production by Leydig cells. This macrophage-derived factor (MDF) is thought to be physiologically relevant, because removal of macrophages from the testis results in altered testosterone secretion and reduced...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2000-03, Vol.141 (3), p.953-958
Hauptverfasser:	Nes, W. David, Lukyanenko, Yevgeniya O., Jia, Zhong Hua, Quideau, Stéphane, Howald, William N., Pratum, Thomas K., West, Robert R., Hutson, James C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioassays Biological activity Cell culture Chromatography Column chromatography Culture media Fertility Gas chromatography High performance liquid chromatography Leydig cells Lipophilic Lipophilicity Liquid chromatography Macrophages Magnetic resonance spectroscopy Mass spectrometry Mass spectroscopy NMR NMR spectroscopy Nuclear magnetic resonance Pattern analysis Peritoneum Physiological effects Secretion Silica Steroidogenesis Testes Testosterone
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