Overexpression of Parathyroid Hormone-Related Protein Enhances Apoptosis in the Rat Intestinal Cell Line, IEC-6

Abstract We used the rat intestinal cell line, IEC-6, to study potential effects of overexpression of PTH-related protein (PTHrP) on apoptosis. A clonal line of PTHrP-overexpressing cells was established by stably transfecting parental cells with PTHrP complementary DNA in a sense orientation (sense...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2001-05, Vol.142 (5), p.1906-1914
Hauptverfasser:	Ye, Yumei, Wang, Cheng, Du, Pingfeng, Falzon, Miriam, Seitz, Patricia K., Cooper, Cary W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acid sequence Amino acids Apoptosis BAX protein Bcl-x protein Cell culture Deoxyribonucleic acid DNA DNA fragmentation Flow cytometry Fluorescence Gene expression Intestine Iodides Localization Parathyroid hormone Parathyroid hormone-related protein Propidium iodide Proteins
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