Production of Immunoreactive Thyroglobulin C-Terminal Fragments during Thyroid Hormone Synthesis

Here, we studied the fragmentation of the prothyroid hormone, thyroglobulin (Tg), which occurs during thyroid hormone synthesis, a process which involves iodide, thyroperoxidase, and the H2O2-generating system, consisting of glucose and glucose oxidase. Various peptides were found to be immunoreacti...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2000-07, Vol.141 (7), p.2518-2525
Hauptverfasser:	Duthoit, Christine, Estienne, Valérie, Delom, Frédéric, Durand-Gorde, Josée-Martine, Mallet, Bernard, Carayon, Pierre, Ruf, Jean
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase Autoantibodies Boring Chemical synthesis Free radicals Glucose oxidase Homology Hormones Hydrogen peroxide Iodide peroxidase Iodides Monoclonal antibodies Oxidation Oxidative stress Peptides Thyroglobulin Thyroid Thyroid hormones
Online-Zugang:	Volltext
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