In vivo regulation of peripheral-type benzodiazepine receptor and glucocorticoid synthesis by Ginkgo biloba extract EGb 761 and isolated ginkgolides

Glucocorticoid excess has broad pathogenic potential including neurotoxicity, neuroendangerment, and immunosuppression. Glucocorticoid synthesis is regulated by ACTH, which acts by accelerating the transport of the precursor cholesterol to the mitochondria where steroidogenesis begins. Ginkgo biloba...

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Veröffentlicht in:	Endocrinology (Philadelphia) 1996-12, Vol.137 (12), p.5707-5718
Hauptverfasser:	Amri, H, Ogwuegbu, S O, Boujrad, N, Drieu, K, Papadopoulos, V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenocorticotropic hormone Benzodiazepine receptors Benzodiazepines Biosynthesis Cholesterol Corticosterone Gene expression Ginkgo biloba Ginkgolides Glucocorticoids Immunosuppression Leaves Neuroprotection Neurotoxicity Protein biosynthesis Proteins Receptors Regulation RNA transport Steroidogenesis Steroidogenic acute regulatory protein
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