Physiological Thyroid Hormone Levels Regulate Numerous Skeletal Muscle Transcripts

ContextSkeletal muscle is an important target tissue for thyroid hormone (TH). It is currently unknown which genes are regulated by physiological TH levels.ObjectiveWe examined the effects of l-thyroxine on human skeletal muscle transcriptome.DesignMicroarray analysis of transcript levels was perfor...

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Veröffentlicht in:	Endocrine reviews 2009-08, Vol.30 (5), p.536-537
Hauptverfasser:	Visser, W. Edward, Heemstra, Karen A, Swagemakers, Sigrid M. A, Özgür, Zeliha, Corssmit, Eleonora P, Burggraaf, Jacobus, van Ijcken, Wilfred F. J, van der Spek, Peter J, Smit, Johannes W. A, Visser, Theo J
Format:	Artikel
Sprache:	eng
Schlagworte:	Biopsy DNA microarrays Energy metabolism Gene expression Gene regulation Genes Human performance Hypothyroidism MicroRNAs miRNA Muscles Musculoskeletal system Patients Physiological effects Physiology Skeletal muscle Statistical methods Thyroid Thyroid carcinoma Thyroid gland Thyroxine Transcriptomes
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