Lyotropic Liquid Crystalline Phase Nanostructure and Cholesterol Enhance Lipid Nanoparticle Mediated mRNA Transfection in Macrophages

Macrophages are unique immune cells attracting growing attention as a potential candidate for cell‐based therapy for infectious diseases and cancer. Strategies that can reprogramme or gene‐edit macrophages hold potential across a spectrum of acute and chronic conditions. Herein, lipid nanoparticles...

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Veröffentlicht in:Advanced functional materials 2024-11, Vol.34 (46), p.n/a
Hauptverfasser: Iscaro, Joshua, Yu, Haitao, Martinez, Natalia, Subramaniam, Santhni, Joyce, Paul, Wang, Hao, Dyett, Brendan P., White, Jacinta, Prestidge, Clive A., Drummond, Calum J., Bozinovski, Steven, Zhai, Jiali
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