Tuning the phototherapeutic activity of Pt( iv ) complexes for bladder cancer via modification of trans N -heterocyclic ligands

Bladder cancer is a common cancer globally that suffers from expensive treatment, drug and hypoxia resistance, and high recurrence rate. A series of six novel diazido Pt( iv ) complexes with the general formula trans , trans , trans -[Pt(N 3 ) 2 (OH) 2 (L) 2 ] and various equatorial N -heterocyclic...

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Veröffentlicht in:	Inorganic chemistry frontiers 2024-11, Vol.11 (22), p.7898-7909
Hauptverfasser:	Shi, Huayun, Clarkson, Guy J., Sadler, Peter J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Accumulation Bladder Bladder cancer Cancer Cytotoxicity Heterocyclic amines Hypoxia Imidazole Ligands Light irradiation Lipids Pyridines Toxicity
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