One-Pot Synthesis and Characterization of Dapsone-Loaded Zeolitic Imidazolate Framework-8

Dapsone (DAP) is used to treat leprosy, a Neglected tropical diseases (NTDs). However, its low solubility often leads to low efficacy. In this work, ZIF-8 nanostructures loaded with DAP (DAP@ZIF-8) were successfully synthesized with suitable drug loading (DL) through a one-pot synthesis. Different p...

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Veröffentlicht in:	Journal of cluster science 2024-12, Vol.35 (8), p.3081-3094
Hauptverfasser:	Diniz, Jocemirlla Marta Correia Tavares, Martins, Jessica Cavalcante, de Melo Amaral, Izabel Maria, Do Amaral, Mylena Karolina Oliveira, da Silva Valeriano, Natalia Michely, Leão, Amanda Damasceno, Dornelas, Camila Braga, Soares-Sobrinho, José Lamartine, Basílio-Júnior, Irinaldo Diniz, Chaves, Luíse Lopes
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioavailability Catalysis Chemical synthesis Chemistry Chemistry and Materials Science Crystal structure Diaminodiphenylsulfone Drug delivery systems Drugs Effectiveness Electron micrographs Infrared spectroscopy Inorganic Chemistry Metal-organic frameworks Methods Molecular interactions Molecular structure Morphology Nanochemistry Nanoparticles Nanotechnology Nitrates Original Paper Physical Chemistry Polydispersity Solvents Spectrum analysis Thermal analysis Thermal stability Toxicity Tropical diseases Zeolites Zeta potential Zinc
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