Lipofibromatous Hamartoma of the Median Nerve: A Case Report

Lipofibromatous hamartoma (LFH) or lipomatosis of the nerve is a benign neoplasm of unclear etiology, which is characterized by fibrofatty proliferation within peripheral nerves. Here, we present a case of a 53-year-old female, right-hand dominant, with chief complaints of a lump in her left palm for many years, and numbness in her thumb, index finger, and middle finger of the left hand past 12 months. According to the patient, the lump has been increasing in size for the last 1 year. The LFH was diagnosed with the help of magnetic resonance imaging images having the presence of thickening of the median nerve, with a coaxial cable-like appearance. The patient was managed surgically through debulking to elevate the pain and numbness. The lack of etiopathogenesis makes the condition difficult to diagnose. Management of LFH is purely based on the extent of the lesion. Conservation of the neurological and sensory function of the nerve while performing surgery was our prime focus. More accurate and reliable tools for diagnosis or precise consensus guidelines will help in early intervention and better outcomes in such patients.