1730-P: In Vitro and In Vivo Effects of Increased IAPP Expression on Human Islet Function

Introduction & Objective: Islet amyloid composed of islet amyloid polypeptide (IAPP) is often present in the pancreas in type 2 diabetes. Cell culture and transgenic rodent models have been used to study islet amyloid toxicity, but less is known about the effects of endogenously-produced IAPP on...

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Veröffentlicht in:Diabetes (New York, N.Y.) N.Y.), 2024-06, Vol.73, p.1
Hauptverfasser: Wright, Jordan J, Jackson, Paige B, Aramandla, Radhika, Davis, Corey, Brissova, Marcela, Powers, Alvin C
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Sprache:eng
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