Astaxanthin production optimization from Rhodosporidium toruloides G17 using potato hydrolysate and its antioxidant activity
Astaxanthin (ASTX), a fat-soluble red pigment, belongs to a group of carotenoids with various compounds that are responsible for biological activities. This research investigated the ASTX production of gamma-mutated yeast strain Rhodosporidium toruloides G17 using potato hydrolysate and urea as repl...
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| Veröffentlicht in: | IOP conference series. Earth and environmental science 2024-09, Vol.1399 (1), p.12009 |
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| creator | Nhung Tran, Tuyet Tran, Ngoc-Tri Nguyen, Tan-Tiep Nguyen, Minh-Phuong Vuong, Tinh-Thi Pham, Quoc-Vu Ngo, Dai-Nghiep |
| description | Astaxanthin (ASTX), a fat-soluble red pigment, belongs to a group of carotenoids with various compounds that are responsible for biological activities. This research investigated the ASTX production of gamma-mutated yeast strain
Rhodosporidium toruloides
G17 using potato hydrolysate and urea as replacement medium components. Under optimal conditions, the gamma-mutated yeast G17 was cultivated in 29.39 g/L total sugar from potato hydrolysate, 1.02 g/L urea as a nitrogen source, 4.09 g/L MgSO
4
, and 10.05% yeast, resulting in the highest ASTX yield of 2,181.14 μg/mL. For the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, at an IC
50
= 9.98 μg/mL, the ASTX crude extract showed greater antioxidant activity than α-tocopherol (IC
50
= 119.66 μg/mL). This research suggests that ASTX from
R. toruloides
G17 is a promising antioxidant agent for nutraceutical and pharmaceutical applications and that potato hydrolysate is an efficient carbon source for yeast culturing in batch mode to obtain ASTX. |
| doi_str_mv | 10.1088/1755-1315/1399/1/012009 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_iop_j</sourceid><recordid>TN_cdi_proquest_journals_3110724584</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3110724584</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1699-c62a7f2453b90d69da4ec28b1080b50871c955413770a98ad79cb51cfcb225aa3</originalsourceid><addsrcrecordid>eNqFkNFLwzAQxosoOKd_gwGfa3Nt0zSPY-gUBoLoc0iT1mWsTU1S2cQ_3tTKfPTpu-Pu-477RdE14FvAZZkAJSSGDEgCGWMJJBhSjNlJNDtOTo81pufRhXNbjAuaZ2wWfS2cF3vR-Y3uUG-NGqTXpkOm97rVn-Knaaxp0fPGKON6Y7XSQ4u8scPOaFU7tAKKBqe7N9QbL7xBm4OyZndwwtdIdApp74KGqL1WQZEINz60P1xGZ43YufrqV-fR6_3dy_IhXj-tHpeLdSyhYCyWRSpok-YkqxhWBVMir2VaVuF9XBFcUpCMkBwySrFgpVCUyYqAbGSVpkSIbB7dTLnhwfehdp5vzWC7cJJnAJiG6DIPW3TaktY4Z-uG91a3wh44YD6i5iNEPgLlI2oOfEIdnNnk1Kb_i_7P9Q2DoINj</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3110724584</pqid></control><display><type>article</type><title>Astaxanthin production optimization from Rhodosporidium toruloides G17 using potato hydrolysate and its antioxidant activity</title><source>IOP Publishing Free Content</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>IOPscience extra</source><creator>Nhung Tran, Tuyet ; Tran, Ngoc-Tri ; Nguyen, Tan-Tiep ; Nguyen, Minh-Phuong ; Vuong, Tinh-Thi ; Pham, Quoc-Vu ; Ngo, Dai-Nghiep</creator><creatorcontrib>Nhung Tran, Tuyet ; Tran, Ngoc-Tri ; Nguyen, Tan-Tiep ; Nguyen, Minh-Phuong ; Vuong, Tinh-Thi ; Pham, Quoc-Vu ; Ngo, Dai-Nghiep</creatorcontrib><description>Astaxanthin (ASTX), a fat-soluble red pigment, belongs to a group of carotenoids with various compounds that are responsible for biological activities. This research investigated the ASTX production of gamma-mutated yeast strain
Rhodosporidium toruloides
G17 using potato hydrolysate and urea as replacement medium components. Under optimal conditions, the gamma-mutated yeast G17 was cultivated in 29.39 g/L total sugar from potato hydrolysate, 1.02 g/L urea as a nitrogen source, 4.09 g/L MgSO
4
, and 10.05% yeast, resulting in the highest ASTX yield of 2,181.14 μg/mL. For the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, at an IC
50
= 9.98 μg/mL, the ASTX crude extract showed greater antioxidant activity than α-tocopherol (IC
50
= 119.66 μg/mL). This research suggests that ASTX from
R. toruloides
G17 is a promising antioxidant agent for nutraceutical and pharmaceutical applications and that potato hydrolysate is an efficient carbon source for yeast culturing in batch mode to obtain ASTX.</description><identifier>ISSN: 1755-1307</identifier><identifier>EISSN: 1755-1315</identifier><identifier>DOI: 10.1088/1755-1315/1399/1/012009</identifier><language>eng</language><publisher>Bristol: IOP Publishing</publisher><subject>antioxidant ; Antioxidants ; Astaxanthin ; Carbon sources ; Carotenoids ; DPPH ; Functional foods & nutraceuticals ; Hydrolysates ; potato hydrolysate ; Potatoes ; Red pigments ; response surface methodology ; Rhodosporidium toruloides ; Tocopherol ; Urea ; Ureas ; Vegetables ; Yeast ; Yeasts</subject><ispartof>IOP conference series. Earth and environmental science, 2024-09, Vol.1399 (1), p.12009</ispartof><rights>Published under licence by IOP Publishing Ltd</rights><rights>Published under licence by IOP Publishing Ltd. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1699-c62a7f2453b90d69da4ec28b1080b50871c955413770a98ad79cb51cfcb225aa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://iopscience.iop.org/article/10.1088/1755-1315/1399/1/012009/pdf$$EPDF$$P50$$Giop$$Hfree_for_read</linktopdf><link.rule.ids>314,776,780,27903,27904,38847,38869,53818,53845</link.rule.ids></links><search><creatorcontrib>Nhung Tran, Tuyet</creatorcontrib><creatorcontrib>Tran, Ngoc-Tri</creatorcontrib><creatorcontrib>Nguyen, Tan-Tiep</creatorcontrib><creatorcontrib>Nguyen, Minh-Phuong</creatorcontrib><creatorcontrib>Vuong, Tinh-Thi</creatorcontrib><creatorcontrib>Pham, Quoc-Vu</creatorcontrib><creatorcontrib>Ngo, Dai-Nghiep</creatorcontrib><title>Astaxanthin production optimization from Rhodosporidium toruloides G17 using potato hydrolysate and its antioxidant activity</title><title>IOP conference series. Earth and environmental science</title><addtitle>IOP Conf. Ser.: Earth Environ. Sci</addtitle><description>Astaxanthin (ASTX), a fat-soluble red pigment, belongs to a group of carotenoids with various compounds that are responsible for biological activities. This research investigated the ASTX production of gamma-mutated yeast strain
Rhodosporidium toruloides
G17 using potato hydrolysate and urea as replacement medium components. Under optimal conditions, the gamma-mutated yeast G17 was cultivated in 29.39 g/L total sugar from potato hydrolysate, 1.02 g/L urea as a nitrogen source, 4.09 g/L MgSO
4
, and 10.05% yeast, resulting in the highest ASTX yield of 2,181.14 μg/mL. For the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, at an IC
50
= 9.98 μg/mL, the ASTX crude extract showed greater antioxidant activity than α-tocopherol (IC
50
= 119.66 μg/mL). This research suggests that ASTX from
R. toruloides
G17 is a promising antioxidant agent for nutraceutical and pharmaceutical applications and that potato hydrolysate is an efficient carbon source for yeast culturing in batch mode to obtain ASTX.</description><subject>antioxidant</subject><subject>Antioxidants</subject><subject>Astaxanthin</subject><subject>Carbon sources</subject><subject>Carotenoids</subject><subject>DPPH</subject><subject>Functional foods & nutraceuticals</subject><subject>Hydrolysates</subject><subject>potato hydrolysate</subject><subject>Potatoes</subject><subject>Red pigments</subject><subject>response surface methodology</subject><subject>Rhodosporidium toruloides</subject><subject>Tocopherol</subject><subject>Urea</subject><subject>Ureas</subject><subject>Vegetables</subject><subject>Yeast</subject><subject>Yeasts</subject><issn>1755-1307</issn><issn>1755-1315</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>O3W</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkNFLwzAQxosoOKd_gwGfa3Nt0zSPY-gUBoLoc0iT1mWsTU1S2cQ_3tTKfPTpu-Pu-477RdE14FvAZZkAJSSGDEgCGWMJJBhSjNlJNDtOTo81pufRhXNbjAuaZ2wWfS2cF3vR-Y3uUG-NGqTXpkOm97rVn-Knaaxp0fPGKON6Y7XSQ4u8scPOaFU7tAKKBqe7N9QbL7xBm4OyZndwwtdIdApp74KGqL1WQZEINz60P1xGZ43YufrqV-fR6_3dy_IhXj-tHpeLdSyhYCyWRSpok-YkqxhWBVMir2VaVuF9XBFcUpCMkBwySrFgpVCUyYqAbGSVpkSIbB7dTLnhwfehdp5vzWC7cJJnAJiG6DIPW3TaktY4Z-uG91a3wh44YD6i5iNEPgLlI2oOfEIdnNnk1Kb_i_7P9Q2DoINj</recordid><startdate>20240901</startdate><enddate>20240901</enddate><creator>Nhung Tran, Tuyet</creator><creator>Tran, Ngoc-Tri</creator><creator>Nguyen, Tan-Tiep</creator><creator>Nguyen, Minh-Phuong</creator><creator>Vuong, Tinh-Thi</creator><creator>Pham, Quoc-Vu</creator><creator>Ngo, Dai-Nghiep</creator><general>IOP Publishing</general><scope>O3W</scope><scope>TSCCA</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>PATMY</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PYCSY</scope></search><sort><creationdate>20240901</creationdate><title>Astaxanthin production optimization from Rhodosporidium toruloides G17 using potato hydrolysate and its antioxidant activity</title><author>Nhung Tran, Tuyet ; Tran, Ngoc-Tri ; Nguyen, Tan-Tiep ; Nguyen, Minh-Phuong ; Vuong, Tinh-Thi ; Pham, Quoc-Vu ; Ngo, Dai-Nghiep</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1699-c62a7f2453b90d69da4ec28b1080b50871c955413770a98ad79cb51cfcb225aa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>antioxidant</topic><topic>Antioxidants</topic><topic>Astaxanthin</topic><topic>Carbon sources</topic><topic>Carotenoids</topic><topic>DPPH</topic><topic>Functional foods & nutraceuticals</topic><topic>Hydrolysates</topic><topic>potato hydrolysate</topic><topic>Potatoes</topic><topic>Red pigments</topic><topic>response surface methodology</topic><topic>Rhodosporidium toruloides</topic><topic>Tocopherol</topic><topic>Urea</topic><topic>Ureas</topic><topic>Vegetables</topic><topic>Yeast</topic><topic>Yeasts</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nhung Tran, Tuyet</creatorcontrib><creatorcontrib>Tran, Ngoc-Tri</creatorcontrib><creatorcontrib>Nguyen, Tan-Tiep</creatorcontrib><creatorcontrib>Nguyen, Minh-Phuong</creatorcontrib><creatorcontrib>Vuong, Tinh-Thi</creatorcontrib><creatorcontrib>Pham, Quoc-Vu</creatorcontrib><creatorcontrib>Ngo, Dai-Nghiep</creatorcontrib><collection>IOP Publishing Free Content</collection><collection>IOPscience (Open Access)</collection><collection>CrossRef</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Environmental Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Environmental Science Collection</collection><jtitle>IOP conference series. Earth and environmental science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nhung Tran, Tuyet</au><au>Tran, Ngoc-Tri</au><au>Nguyen, Tan-Tiep</au><au>Nguyen, Minh-Phuong</au><au>Vuong, Tinh-Thi</au><au>Pham, Quoc-Vu</au><au>Ngo, Dai-Nghiep</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Astaxanthin production optimization from Rhodosporidium toruloides G17 using potato hydrolysate and its antioxidant activity</atitle><jtitle>IOP conference series. Earth and environmental science</jtitle><addtitle>IOP Conf. Ser.: Earth Environ. Sci</addtitle><date>2024-09-01</date><risdate>2024</risdate><volume>1399</volume><issue>1</issue><spage>12009</spage><pages>12009-</pages><issn>1755-1307</issn><eissn>1755-1315</eissn><abstract>Astaxanthin (ASTX), a fat-soluble red pigment, belongs to a group of carotenoids with various compounds that are responsible for biological activities. This research investigated the ASTX production of gamma-mutated yeast strain
Rhodosporidium toruloides
G17 using potato hydrolysate and urea as replacement medium components. Under optimal conditions, the gamma-mutated yeast G17 was cultivated in 29.39 g/L total sugar from potato hydrolysate, 1.02 g/L urea as a nitrogen source, 4.09 g/L MgSO
4
, and 10.05% yeast, resulting in the highest ASTX yield of 2,181.14 μg/mL. For the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, at an IC
50
= 9.98 μg/mL, the ASTX crude extract showed greater antioxidant activity than α-tocopherol (IC
50
= 119.66 μg/mL). This research suggests that ASTX from
R. toruloides
G17 is a promising antioxidant agent for nutraceutical and pharmaceutical applications and that potato hydrolysate is an efficient carbon source for yeast culturing in batch mode to obtain ASTX.</abstract><cop>Bristol</cop><pub>IOP Publishing</pub><doi>10.1088/1755-1315/1399/1/012009</doi><tpages>14</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | antioxidant Antioxidants Astaxanthin Carbon sources Carotenoids DPPH Functional foods & nutraceuticals Hydrolysates potato hydrolysate Potatoes Red pigments response surface methodology Rhodosporidium toruloides Tocopherol Urea Ureas Vegetables Yeast Yeasts |
| title | Astaxanthin production optimization from Rhodosporidium toruloides G17 using potato hydrolysate and its antioxidant activity |
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