Brain‐Targeted 9‐Phenanthrol‐Loaded Lipid Nanoparticle Prevents Brain Edema after Cerebral Ischemia‐Reperfusion Injury by Inhibiting the Trpm4 Channel in Mice

Brain edema robustly increases mortality and hinders functional recovery after acute ischemic stroke. However, there are currently no effective therapies available for treating or preventing it. The unchecked opening of the transient receptor potential M4 (TRPM4) channel results in an excessive infl...

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Veröffentlicht in:	Advanced functional materials 2024-09, Vol.34 (36), p.n/a
Hauptverfasser:	Liu, Kewei, Peng, Yuqin, Xu, Mingheng, Yuan, Kun, Li, Yongchuan, Lin, Chuman, Zhao, Xiaolin, Zhu, Juan, Chang, Yuan, Lin, Zhenzhou, Pan, Suyue, Ma, Huanrong, Wang, Xiaorui, Huang, Kaibin
Format:	Artikel
Sprache:	eng
Schlagworte:	9‐phenanthrol Biocompatibility Brain brain edema Edema Free radicals Injury prevention Ischemia ischemic stroke lipid nanoparticles Lipids Nanoparticles Occlusion Oxygen Recovery Stroke SUR1‐TRPM4
Online-Zugang:	Volltext
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