Small intestine submucosa decorated 3D printed scaffold accelerated diabetic bone regeneration by ameliorating the microenvironment

The 3D printed scaffolds constructed from polymers have shown significant potential in the field of bone defect regeneration. However, the efficacy of these scaffolds can be markedly reduced in certain pathological conditions like diabetes, where an altered inflammatory microenvironment and diminish...

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Veröffentlicht in:	Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2024-09, Vol.12 (37), p.9375-9389
Hauptverfasser:	Tan, Jie, Chen, Zecai, Xu, Zhen, Huang, Yafang, Qin, Lei, Long, Yufeng, Wu, Jiayi, Yang, Hantao, Chen, Xuandu, Yi, Weihong, Hang, Ruiqiang, Guan, Min, Wang, Huaiyu, Gao, Ang, Yang, Dazhi
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Biological activity Blood vessels Bone growth Defects Diabetes Diabetes mellitus Extracellular matrix Hydroxyapatite In vivo methods and tests Inflammation Intestine Leukocyte migration Macrophages Mechanical properties Performance degradation Phenotypes Poly(lactide-co-glycolide) Polylactide-co-glycolide Polymers Regeneration Regeneration (physiology) Regenerative medicine Scaffolds Small intestine Synergistic effect Three dimensional printing Tissue engineering
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