When and How Telomeres Lengthen in Development and Cell Lines: Evolution of Olovnikov’s Telomere Theory

Telomeres are special nucleoprotein structures that protect the ends of linear chromosomes. Telomeric DNA is composed of 6-nucleotide repeats that are synthesized by telomerase, a specialized DNA polymerase. According to Alexey Olovnikov’s telomere theory of aging, replicative aging in somatic cells...

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Veröffentlicht in:	Russian journal of developmental biology 2024-04, Vol.55 (2), p.39-56
1. Verfasser:	Kalmykova, A. I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animal Anatomy Biomedical and Life Sciences Cell division Developmental Biology DNA-directed DNA polymerase Embryo cells Embryogenesis Gametogenesis Germ cells Histology Homologous recombination Life Sciences Morphology Pluripotency Reviews Somatic cells Stem cells Telomerase Telomeres Tumor cells Yeast
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