Changes in structural plasticity of hippocampal neurons in an animal model of multiple sclerosis

Structural plasticity is critical for the functional diversity of neurons in the brain. Experimental autoimmune encephalomyelitis (EAE) is the most commonly used model for multiple sclerosis (MS), successfully mimicking its key pathological features (inflammation, demyelination, axonal loss, and gli...

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Veröffentlicht in:	Dōngwùxué yánjiū 2024-03, Vol.45 (2), p.398-414
Hauptverfasser:	Weerasinghe-Mudiyanselage, Poornima D E, Kang, Sohi, Kim, Joong-Sun, Kim, Sung-Ho, Wang, Hongbing, Shin, Taekyun, Moon, Changjong
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Ammon's horn Animal cognition Animal models Animals ARC protein Axonal plasticity Behavioral plasticity Brain Complexity Cytokines Cytokines - metabolism Cytoskeleton Demyelination Dendritic spines Dendritic structure Dentate gyrus Encephalomyelitis Encephalomyelitis, Autoimmune, Experimental - metabolism Encephalomyelitis, Autoimmune, Experimental - pathology Encephalomyelitis, Autoimmune, Experimental - veterinary Engines Experimental allergic encephalomyelitis Extracellular signal-regulated kinase Field tests Functional plasticity Glial cells Gliosis Hippocampal plasticity Hippocampus Hippocampus - metabolism Immunization Inflammation Kinases Laboratory animals Memory Mice mRNA Multiple sclerosis Multiple Sclerosis - metabolism Multiple Sclerosis - pathology Multiple Sclerosis - veterinary Neuronal-glial interactions Neurons Neurons - pathology Neuroplasticity Pathogenesis Peptides Phosphorylation Plasticity Rodent Diseases - metabolism Rodent Diseases - pathology Spine Synaptic plasticity
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