A Live Cell Imaging Microfluidic Model for Studying Extravasation of Bloodborne Bacterial Pathogens

Bacteria that migrate (extravasate) out of the bloodstream during vascular dissemination can cause secondary infections in many tissues and organs, including the brain, heart, liver, joints, and bone with clinically serious and sometimes fatal outcomes. The mechanisms by which bacteria extravasate t...

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Veröffentlicht in:	Cellular microbiology 2022-09, Vol.2022, p.1-12
Hauptverfasser:	Bergevin, Michele d., Boczula, Anna E., Caruso, Laura-lee, Persson, Henrik, Simmons, Craig A., Moriarty, Tara J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Bacterial infections Blood flow Blood vessels Bone blood flow Bone imaging Cancer Cardiovascular system Endothelial cells Endothelium Extravasation Hydrogels In vivo methods and tests Leukocytes Lyme disease Measurement methods Medical imaging Microfluidics Microscopy Neuroimaging Pathogens Physiology Plasma Polyethylene terephthalate Reynolds number Shear stress Vector-borne diseases Visualization
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