Convenient syntheses of 2-acylamino-4-halothiazoles and acylated derivatives using a versatile Boc-intermediate

The 2-aminothiazole grouping is a significant feature of many series of biologically active molecules, including antibiotics, anticancer agents and NSAIDs. We have a longstanding interest in the synthesis and biological evaluation of thiazolides, viz. [2-hydroxyaroyl- N -(thiazol-2-yl)-amides] which...

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Veröffentlicht in:RSC advances 2024-08, Vol.14 (38), p.27894-2793
Hauptverfasser: Pate, Sophie, Taujanskas, Joshua, Wells, Robyn, Robertson, Craig M, O'Neill, Paul M, Stachulski, Andrew V
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Sprache:eng
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