302-OR: The Antimyostatin Antibody SRK-439 Promotes Healthy Body Composition in Combination with GLP-1RAs in a Mouse Model of Obesity

One of the challenges with obesity treatments is maintaining a healthy body composition during weight loss; lean mass is reduced during weight loss (15%-40% of total weight lost) which may impact long-term durability and health benefits. Identifying an agent that safely maintains lean mass during ob...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2024-06, Vol.73, p.1
Hauptverfasser:	Fulham, Melissa A, Chapron, Christopher, Danehy, Francis T, Streich, Frederick C, Liang, Brian, Boston, Christopher J, Jackson, Justin W, Huang, Yan, Nicholls, Samantha EB, Cortes, Leslie, Qatanani, Mo
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Body composition Body fat Body weight Body weight loss Glucagon Glucagon-like peptide 1 Immunoglobulin G Leptin Myostatin Obesity Weight control
Online-Zugang:	Volltext
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