1808-LB: NIK-Mediated Microglia Polarization Induces Endothelial Dysfunction in Diabetic Retinopathy

Introduction & Objective: Chronic inflammation significantly contributes to endothelial dysfunction in diabetic retinopathy (DR). NIK, a central and specific signal component that regulates the activation of noncanonical NF-κB pathway, is overexpressed in inflammatory diseases, metabolic disorde...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2024-06, Vol.73 (Supplement_1), p.1
Hauptverfasser:	LI, HONGXUE, KUANG, HONGYU
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell culture Cell permeability Diabetes Diabetes mellitus Diabetic retinopathy Endothelial cells Enzyme-linked immunosorbent assay High fat diet Immunofluorescence Immunohistochemistry Inflammatory diseases Metabolic disorders Metabolic rate Microglia Microvasculature NF-κB protein Permeability Polarization Retinopathy Streptozocin Western blotting
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