An evaluation of the recommendations for primary nutrition research addressing noncommunicable disease using the EPICOT+ framework: A cross‐sectional descriptive meta‐research study of Cochrane nutrition systematic reviews

Background Noncommunicable diseases (NCDs) are a global health problem and many risk factors associated with the development of NCDs are related to nutrition. Aims This study aimed to describe and summarize the research recommendations for primary research made in Cochrane nutrition systematic revie...

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Veröffentlicht in:Cochrane evidence synthesis and methods 2024-03, Vol.2 (3), p.n/a
Hauptverfasser: Ruzive, Sheena, Theunissen, Helene, Durão, Solange, Visser, Marianne E., Naude, Celeste E.
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creator Ruzive, Sheena
Theunissen, Helene
Durão, Solange
Visser, Marianne E.
Naude, Celeste E.
description Background Noncommunicable diseases (NCDs) are a global health problem and many risk factors associated with the development of NCDs are related to nutrition. Aims This study aimed to describe and summarize the research recommendations for primary research made in Cochrane nutrition systematic reviews (SRs) addressing NCDs, according to the evidence, population, intervention, comparison, outcome, time stamp (date of search), study design, time frame (length of follow‐up) and burden of disease (EPICOT+) framework. Materials & Methods We screened a database of Cochrane nutrition SRs (n = 692) in March 2021 to identify those SRs addressing the four main NCDs (cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes) and their nutrition‐related risk factors (obesity, unhealthy diets). The “implications for research” sections of included SRs (and the “search methods” sections for the time stamp item) were analyzed using EPICOT+. Results We included 150/692 SRs; most addressed cardiovascular diseases (38.6%), and cancer (17.3%). The EPICOT+ items with the most reported research recommendations were time stamp (98.7%), intervention (94.7%), study design (89.3%), and outcomes (86%), and the least reported were the time frame (52%), comparison (30%), and burden of disease (8%). Most SRs recommended more studies overall (98.7%), assessing specific interventions (93.3%) (e.g., specific foods/food groups and diets/dietary patterns, micronutrient/complementary supplements, nutrition education techniques, and policies/programs) and a range of clinical and patient‐related outcomes (84.7%). Recommendations related to study design and quality included the need for more randomized (72.7%), better quality (55.3%), larger (44.7%), and better reported (26%) studies with a long‐term duration of follow‐up (50.7%). Discussion Our findings show that research recommendations reported in Cochrane nutrition SRs addressing the four major NCDs and their nutrition‐related risk factors largely followed the EPICOT+ framework. For example, items that could be improved upon were the comparison and time frame items. Conclusion These recommendations could contribute more significantly to planning future primary studies addressing important evidence gaps and limitations in the current evidence base. Plain Language Summary Noncommunicable diseases (NCDs), or chronic diseases, are a global health problem. NCDs include heart disease, cancer, chronic respiratory disease, and dia
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Aims This study aimed to describe and summarize the research recommendations for primary research made in Cochrane nutrition systematic reviews (SRs) addressing NCDs, according to the evidence, population, intervention, comparison, outcome, time stamp (date of search), study design, time frame (length of follow‐up) and burden of disease (EPICOT+) framework. Materials &amp; Methods We screened a database of Cochrane nutrition SRs (n = 692) in March 2021 to identify those SRs addressing the four main NCDs (cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes) and their nutrition‐related risk factors (obesity, unhealthy diets). The “implications for research” sections of included SRs (and the “search methods” sections for the time stamp item) were analyzed using EPICOT+. Results We included 150/692 SRs; most addressed cardiovascular diseases (38.6%), and cancer (17.3%). The EPICOT+ items with the most reported research recommendations were time stamp (98.7%), intervention (94.7%), study design (89.3%), and outcomes (86%), and the least reported were the time frame (52%), comparison (30%), and burden of disease (8%). Most SRs recommended more studies overall (98.7%), assessing specific interventions (93.3%) (e.g., specific foods/food groups and diets/dietary patterns, micronutrient/complementary supplements, nutrition education techniques, and policies/programs) and a range of clinical and patient‐related outcomes (84.7%). Recommendations related to study design and quality included the need for more randomized (72.7%), better quality (55.3%), larger (44.7%), and better reported (26%) studies with a long‐term duration of follow‐up (50.7%). Discussion Our findings show that research recommendations reported in Cochrane nutrition SRs addressing the four major NCDs and their nutrition‐related risk factors largely followed the EPICOT+ framework. For example, items that could be improved upon were the comparison and time frame items. Conclusion These recommendations could contribute more significantly to planning future primary studies addressing important evidence gaps and limitations in the current evidence base. Plain Language Summary Noncommunicable diseases (NCDs), or chronic diseases, are a global health problem. NCDs include heart disease, cancer, chronic respiratory disease, and diabetes. Many of the factors associated with the development of NCDs are related to nutrition. In a database of Cochrane nutrition systematic reviews (SRs) (n = 692) we identified 150 SRs, focusing on four types of NCDs (cardiovascular diseases, e.g., heart attacks and stroke, cancer, chronic respiratory disease, e.g., asthma and diabetes), and their nutrition‐related risk factors (obesity, unhealthy diets). We analyzed certain sections of these SRs to see whether the authors included certain items from the EPICOT+ framework. This framework is used for creating or finding the best practice evidence‐based research. This includes reference to the evidence, population, intervention, comparison, outcome, date of search, study design, duration of follow‐up, and burden of disease in their recommendations and search methods. We found that almost all SRs reported the literature search date (98.7%), the intervention(s) that need to be examined (94.7%), the study design(s) that would work best (89.3%), and the outcome(s) that need to be measured (86%) in future studies. Fewer authors described how long study participants should be followed up for (52%), the intervention(s) against which the intervention of interest needs to be compared to in future studies (30%) and the burden of disease or condition being addressed (8%). We also analyzed what the authors recommended. Most SRs recommended more studies on whether the specific foods or food groups, diets or dietary patterns, micronutrient or complementary supplements, nutrition education techniques, and policies or programs work for a variety of clinical and patient‐relevant outcomes. Many authors recommended large, randomized studies, with better quality and reporting, and following study participants for long periods of time. Our findings show that research recommendations reported by authors of Cochrane nutrition SRs largely followed the EPICOT+ framework. For example, items that could be improved were the comparison and the time frame items. Our summary of their recommendations could help with planning of future studies by showing where important gaps in the current nutrition evidence are.</description><identifier>ISSN: 2832-9023</identifier><identifier>EISSN: 2832-9023</identifier><identifier>DOI: 10.1002/cesm.12048</identifier><language>eng</language><publisher>East Lansing: John Wiley &amp; Sons, Inc</publisher><subject>Alcohol use ; Cancer ; Cochrane systematic reviews ; Diabetes ; Disease prevention ; EPICOT+ framework ; Food ; Mortality ; noncommunicable disease ; nutrition ; Nutrition research ; Obesity ; research recommendations ; Respiratory diseases ; Risk factors</subject><ispartof>Cochrane evidence synthesis and methods, 2024-03, Vol.2 (3), p.n/a</ispartof><rights>2024 The Authors. published by John Wiley &amp; Sons Ltd on behalf of The Cochrane Collaboration.</rights><rights>2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the "License"). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1418-198f8a8d26cc39c851daa45c9f4590b0eb4930812cd78438167c01d155912bb93</cites><orcidid>0000-0001-9552-5245</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fcesm.12048$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fcesm.12048$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,11541,27901,27902,46027,46451</link.rule.ids></links><search><creatorcontrib>Ruzive, Sheena</creatorcontrib><creatorcontrib>Theunissen, Helene</creatorcontrib><creatorcontrib>Durão, Solange</creatorcontrib><creatorcontrib>Visser, Marianne E.</creatorcontrib><creatorcontrib>Naude, Celeste E.</creatorcontrib><title>An evaluation of the recommendations for primary nutrition research addressing noncommunicable disease using the EPICOT+ framework: A cross‐sectional descriptive meta‐research study of Cochrane nutrition systematic reviews</title><title>Cochrane evidence synthesis and methods</title><description>Background Noncommunicable diseases (NCDs) are a global health problem and many risk factors associated with the development of NCDs are related to nutrition. Aims This study aimed to describe and summarize the research recommendations for primary research made in Cochrane nutrition systematic reviews (SRs) addressing NCDs, according to the evidence, population, intervention, comparison, outcome, time stamp (date of search), study design, time frame (length of follow‐up) and burden of disease (EPICOT+) framework. Materials &amp; Methods We screened a database of Cochrane nutrition SRs (n = 692) in March 2021 to identify those SRs addressing the four main NCDs (cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes) and their nutrition‐related risk factors (obesity, unhealthy diets). The “implications for research” sections of included SRs (and the “search methods” sections for the time stamp item) were analyzed using EPICOT+. Results We included 150/692 SRs; most addressed cardiovascular diseases (38.6%), and cancer (17.3%). The EPICOT+ items with the most reported research recommendations were time stamp (98.7%), intervention (94.7%), study design (89.3%), and outcomes (86%), and the least reported were the time frame (52%), comparison (30%), and burden of disease (8%). Most SRs recommended more studies overall (98.7%), assessing specific interventions (93.3%) (e.g., specific foods/food groups and diets/dietary patterns, micronutrient/complementary supplements, nutrition education techniques, and policies/programs) and a range of clinical and patient‐related outcomes (84.7%). Recommendations related to study design and quality included the need for more randomized (72.7%), better quality (55.3%), larger (44.7%), and better reported (26%) studies with a long‐term duration of follow‐up (50.7%). Discussion Our findings show that research recommendations reported in Cochrane nutrition SRs addressing the four major NCDs and their nutrition‐related risk factors largely followed the EPICOT+ framework. For example, items that could be improved upon were the comparison and time frame items. Conclusion These recommendations could contribute more significantly to planning future primary studies addressing important evidence gaps and limitations in the current evidence base. Plain Language Summary Noncommunicable diseases (NCDs), or chronic diseases, are a global health problem. NCDs include heart disease, cancer, chronic respiratory disease, and diabetes. Many of the factors associated with the development of NCDs are related to nutrition. In a database of Cochrane nutrition systematic reviews (SRs) (n = 692) we identified 150 SRs, focusing on four types of NCDs (cardiovascular diseases, e.g., heart attacks and stroke, cancer, chronic respiratory disease, e.g., asthma and diabetes), and their nutrition‐related risk factors (obesity, unhealthy diets). We analyzed certain sections of these SRs to see whether the authors included certain items from the EPICOT+ framework. This framework is used for creating or finding the best practice evidence‐based research. This includes reference to the evidence, population, intervention, comparison, outcome, date of search, study design, duration of follow‐up, and burden of disease in their recommendations and search methods. We found that almost all SRs reported the literature search date (98.7%), the intervention(s) that need to be examined (94.7%), the study design(s) that would work best (89.3%), and the outcome(s) that need to be measured (86%) in future studies. Fewer authors described how long study participants should be followed up for (52%), the intervention(s) against which the intervention of interest needs to be compared to in future studies (30%) and the burden of disease or condition being addressed (8%). We also analyzed what the authors recommended. Most SRs recommended more studies on whether the specific foods or food groups, diets or dietary patterns, micronutrient or complementary supplements, nutrition education techniques, and policies or programs work for a variety of clinical and patient‐relevant outcomes. Many authors recommended large, randomized studies, with better quality and reporting, and following study participants for long periods of time. Our findings show that research recommendations reported by authors of Cochrane nutrition SRs largely followed the EPICOT+ framework. For example, items that could be improved were the comparison and the time frame items. Our summary of their recommendations could help with planning of future studies by showing where important gaps in the current nutrition evidence are.</description><subject>Alcohol use</subject><subject>Cancer</subject><subject>Cochrane systematic reviews</subject><subject>Diabetes</subject><subject>Disease prevention</subject><subject>EPICOT+ framework</subject><subject>Food</subject><subject>Mortality</subject><subject>noncommunicable disease</subject><subject>nutrition</subject><subject>Nutrition research</subject><subject>Obesity</subject><subject>research recommendations</subject><subject>Respiratory diseases</subject><subject>Risk factors</subject><issn>2832-9023</issn><issn>2832-9023</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kcFu1DAQhiMEElXphSewxA20ZWwnuza3VbRApaJWopwjx56wLom9eJJd7Y1H4Bn7JCTZCvXUk0eeb37_4z_L3nK45ADio0XqLrmAXL3IzoSSYqFByJdP6tfZBdE9AEgAtdLyLHtYB4Z70w6m9zGw2LB-iyyhjV2Hwc23xJqY2C75zqQjC0Of_AwnJDTJbplxbqzJh58sxDCNDsFbU7fInB8ZQjbM3Ul7c3tV3tx9YE0yHR5i-vWJrZlNkejhz19CO0mbljkkm_yu93tkHfZmbP5_j_rBHSevZbTbZAI-MUVH6rEbfdvR397jgd5krxrTEl48nufZj8-bu_Lr4vrmy1W5vl5YnnO14Fo1yignltZKbVXBnTF5YXWTFxpqwDrXEhQX1q1ULhVfrixwx4tCc1HXWp5n7066uxR_D0h9dR-HNO5ClQQNcglSFCP1_kTNKydsqsePrThUU4zVFGM1xzjC_AQffIvHZ8iq3Hz_dpr5B8kZp8I</recordid><startdate>202403</startdate><enddate>202403</enddate><creator>Ruzive, Sheena</creator><creator>Theunissen, Helene</creator><creator>Durão, Solange</creator><creator>Visser, Marianne E.</creator><creator>Naude, Celeste E.</creator><general>John Wiley &amp; 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Aims This study aimed to describe and summarize the research recommendations for primary research made in Cochrane nutrition systematic reviews (SRs) addressing NCDs, according to the evidence, population, intervention, comparison, outcome, time stamp (date of search), study design, time frame (length of follow‐up) and burden of disease (EPICOT+) framework. Materials &amp; Methods We screened a database of Cochrane nutrition SRs (n = 692) in March 2021 to identify those SRs addressing the four main NCDs (cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes) and their nutrition‐related risk factors (obesity, unhealthy diets). The “implications for research” sections of included SRs (and the “search methods” sections for the time stamp item) were analyzed using EPICOT+. Results We included 150/692 SRs; most addressed cardiovascular diseases (38.6%), and cancer (17.3%). The EPICOT+ items with the most reported research recommendations were time stamp (98.7%), intervention (94.7%), study design (89.3%), and outcomes (86%), and the least reported were the time frame (52%), comparison (30%), and burden of disease (8%). Most SRs recommended more studies overall (98.7%), assessing specific interventions (93.3%) (e.g., specific foods/food groups and diets/dietary patterns, micronutrient/complementary supplements, nutrition education techniques, and policies/programs) and a range of clinical and patient‐related outcomes (84.7%). Recommendations related to study design and quality included the need for more randomized (72.7%), better quality (55.3%), larger (44.7%), and better reported (26%) studies with a long‐term duration of follow‐up (50.7%). Discussion Our findings show that research recommendations reported in Cochrane nutrition SRs addressing the four major NCDs and their nutrition‐related risk factors largely followed the EPICOT+ framework. For example, items that could be improved upon were the comparison and time frame items. Conclusion These recommendations could contribute more significantly to planning future primary studies addressing important evidence gaps and limitations in the current evidence base. Plain Language Summary Noncommunicable diseases (NCDs), or chronic diseases, are a global health problem. NCDs include heart disease, cancer, chronic respiratory disease, and diabetes. Many of the factors associated with the development of NCDs are related to nutrition. In a database of Cochrane nutrition systematic reviews (SRs) (n = 692) we identified 150 SRs, focusing on four types of NCDs (cardiovascular diseases, e.g., heart attacks and stroke, cancer, chronic respiratory disease, e.g., asthma and diabetes), and their nutrition‐related risk factors (obesity, unhealthy diets). We analyzed certain sections of these SRs to see whether the authors included certain items from the EPICOT+ framework. This framework is used for creating or finding the best practice evidence‐based research. This includes reference to the evidence, population, intervention, comparison, outcome, date of search, study design, duration of follow‐up, and burden of disease in their recommendations and search methods. We found that almost all SRs reported the literature search date (98.7%), the intervention(s) that need to be examined (94.7%), the study design(s) that would work best (89.3%), and the outcome(s) that need to be measured (86%) in future studies. Fewer authors described how long study participants should be followed up for (52%), the intervention(s) against which the intervention of interest needs to be compared to in future studies (30%) and the burden of disease or condition being addressed (8%). We also analyzed what the authors recommended. Most SRs recommended more studies on whether the specific foods or food groups, diets or dietary patterns, micronutrient or complementary supplements, nutrition education techniques, and policies or programs work for a variety of clinical and patient‐relevant outcomes. Many authors recommended large, randomized studies, with better quality and reporting, and following study participants for long periods of time. Our findings show that research recommendations reported by authors of Cochrane nutrition SRs largely followed the EPICOT+ framework. For example, items that could be improved were the comparison and the time frame items. Our summary of their recommendations could help with planning of future studies by showing where important gaps in the current nutrition evidence are.</abstract><cop>East Lansing</cop><pub>John Wiley &amp; Sons, Inc</pub><doi>10.1002/cesm.12048</doi><tpages>17</tpages><orcidid>https://orcid.org/0000-0001-9552-5245</orcidid><oa>free_for_read</oa></addata></record>
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subjects Alcohol use
Cancer
Cochrane systematic reviews
Diabetes
Disease prevention
EPICOT+ framework
Food
Mortality
noncommunicable disease
nutrition
Nutrition research
Obesity
research recommendations
Respiratory diseases
Risk factors
title An evaluation of the recommendations for primary nutrition research addressing noncommunicable disease using the EPICOT+ framework: A cross‐sectional descriptive meta‐research study of Cochrane nutrition systematic reviews
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