Vitamin D supplementation reduces systemic modulation of oxidative stress and collagen degradation in keratoconus patients

Vitamin D supplementation reduces systemic modulation of oxidative stress and collagen degradation in keratoconus patients

Aims/Purpose: To assess whether vitamin D (Vit D) supplementation modulates systemic biomarkers involved in collagen degradation and oxidative stress in adolescent patients affected with keratoconus (KC). Methods: This study included forty adolescent patients (age range: 16–19 years) with KC and Vit...

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Veröffentlicht in:Acta ophthalmologica (Oxford, England) England), 2024-01, Vol.102 (S279), p.n/a
Hauptverfasser: Suanno, Giuseppe, Vitar, Romina Mayra Lasagni, Fonteyne, Philippe, Knutsson, Karl Anders, Bertuzzi, Federico, Galli, Laura, Rama, Paolo, Ferrari, Giulio
Format: Artikel
Sprache:eng
Schlagworte:
Catabolism
Collagen
Collagen (type I)
Degradation
Dietary supplements
Keratoconus
Oxidative stress
Peroxisome proliferator-activated receptors
Vitamin D
Vitamin D receptors
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Zusammenfassung:Aims/Purpose: To assess whether vitamin D (Vit D) supplementation modulates systemic biomarkers involved in collagen degradation and oxidative stress in adolescent patients affected with keratoconus (KC). Methods: This study included forty adolescent patients (age range: 16–19 years) with KC and Vit D insufficiency (
ISSN:1755-375X
1755-3768
DOI:10.1111/aos.16064