Pharmacological and phytochemical review of Acmella oleracea: a comprehensive analysis of its therapeutic potential
Acmella oleracea L. (Asteraceae), commonly known as the toothache plant, is a tropical herb with significant therapeutic potential. Traditionally, it has been used for its analgesic and sialagogue properties, and it is known for its distinctive yellow flower crest. This review addresses current gaps...
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| Veröffentlicht in: | Discover Applied Sciences 2024-07, Vol.6 (8), p.412, Article 412 |
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| creator | Aktar, Mst. Asma Bhuia, Md. Shimul Molla, Shamim Chowdhury, Raihan Sarkar, Chandan Al Shahariar, Md Roy, Pias Reiner, Željko Sharifi-Rad, Javad Calina, Daniela Shakil, Md. Abdul Kader Islam, Muhammad Torequl |
| description | Acmella oleracea
L. (Asteraceae), commonly known as the toothache plant, is a tropical herb with significant therapeutic potential. Traditionally, it has been used for its analgesic and sialagogue properties, and it is known for its distinctive yellow flower crest. This review addresses current gaps in the understanding of its pharmacological properties and aims to provide a comprehensive analysis of its therapeutic potential. A thorough literature review was conducted using databases such as Google Scholar, ScienceDirect, and PubMed/MedLine. The findings indicate that A
. oleracea
contains a variety of phytochemicals, including spilanthol, which exhibit diverse pharmacological activities such as antioxidant, anti-inflammatory, immunomodulatory, antinociceptive, pronociceptive, antibacterial, antifungal, antidiabetic, diuretic, and vasorelaxant effects. The results highlight the significant medicinal potential of
A. oleracea
while also identifying areas for further research, particularly regarding its toxicological impacts on humans and animals. This review aims to guide future studies on the health benefits and safety of this plant.
Article Highlights
Acmella oleracea
exhibits significant pain-relieving properties, interacting with pain receptors effectively.
The plant's extracts show strong antimicrobial effects, useful against various bacterial infections.
Acmella oleracea
demonstrates potent antioxidant and antifungal activities, promoting health and disease prevention. |
| doi_str_mv | 10.1007/s42452-024-06108-5 |
| format | Article |
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L. (Asteraceae), commonly known as the toothache plant, is a tropical herb with significant therapeutic potential. Traditionally, it has been used for its analgesic and sialagogue properties, and it is known for its distinctive yellow flower crest. This review addresses current gaps in the understanding of its pharmacological properties and aims to provide a comprehensive analysis of its therapeutic potential. A thorough literature review was conducted using databases such as Google Scholar, ScienceDirect, and PubMed/MedLine. The findings indicate that A
. oleracea
contains a variety of phytochemicals, including spilanthol, which exhibit diverse pharmacological activities such as antioxidant, anti-inflammatory, immunomodulatory, antinociceptive, pronociceptive, antibacterial, antifungal, antidiabetic, diuretic, and vasorelaxant effects. The results highlight the significant medicinal potential of
A. oleracea
while also identifying areas for further research, particularly regarding its toxicological impacts on humans and animals. This review aims to guide future studies on the health benefits and safety of this plant.
Article Highlights
Acmella oleracea
exhibits significant pain-relieving properties, interacting with pain receptors effectively.
The plant's extracts show strong antimicrobial effects, useful against various bacterial infections.
Acmella oleracea
demonstrates potent antioxidant and antifungal activities, promoting health and disease prevention.</description><identifier>ISSN: 3004-9261</identifier><identifier>ISSN: 2523-3963</identifier><identifier>EISSN: 3004-9261</identifier><identifier>EISSN: 2523-3971</identifier><identifier>DOI: 10.1007/s42452-024-06108-5</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Acmella oleracea ; Analgesics ; Antiinfectives and antibacterials ; Antimicrobial activity ; Antioxidants ; Applied and Technical Physics ; Bacterial diseases ; Chemistry/Food Science ; Diabetes mellitus ; Diuretics ; Earth Sciences ; Engineering ; Environment ; Flowers & plants ; Free radicals ; Fungicides ; Health promotion ; Immunomodulation ; Infections ; Insecticides ; Laboratory animals ; Literature reviews ; Materials Science ; Medicinal plants ; Pain ; Pain perception ; Pharmacology ; Phytochemicals ; Plant extracts ; Receptor mechanisms ; Review ; Taxonomy ; Ulcers</subject><ispartof>Discover Applied Sciences, 2024-07, Vol.6 (8), p.412, Article 412</ispartof><rights>The Author(s) 2024</rights><rights>The Author(s) 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c244t-1f576d75393dc0af1c433920c6123506f3cebe3ea14314a8e8f7b943286f67903</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,861,27905,27906</link.rule.ids></links><search><creatorcontrib>Aktar, Mst. Asma</creatorcontrib><creatorcontrib>Bhuia, Md. Shimul</creatorcontrib><creatorcontrib>Molla, Shamim</creatorcontrib><creatorcontrib>Chowdhury, Raihan</creatorcontrib><creatorcontrib>Sarkar, Chandan</creatorcontrib><creatorcontrib>Al Shahariar, Md</creatorcontrib><creatorcontrib>Roy, Pias</creatorcontrib><creatorcontrib>Reiner, Željko</creatorcontrib><creatorcontrib>Sharifi-Rad, Javad</creatorcontrib><creatorcontrib>Calina, Daniela</creatorcontrib><creatorcontrib>Shakil, Md. Abdul Kader</creatorcontrib><creatorcontrib>Islam, Muhammad Torequl</creatorcontrib><title>Pharmacological and phytochemical review of Acmella oleracea: a comprehensive analysis of its therapeutic potential</title><title>Discover Applied Sciences</title><addtitle>Discov Appl Sci</addtitle><description>Acmella oleracea
L. (Asteraceae), commonly known as the toothache plant, is a tropical herb with significant therapeutic potential. Traditionally, it has been used for its analgesic and sialagogue properties, and it is known for its distinctive yellow flower crest. This review addresses current gaps in the understanding of its pharmacological properties and aims to provide a comprehensive analysis of its therapeutic potential. A thorough literature review was conducted using databases such as Google Scholar, ScienceDirect, and PubMed/MedLine. The findings indicate that A
. oleracea
contains a variety of phytochemicals, including spilanthol, which exhibit diverse pharmacological activities such as antioxidant, anti-inflammatory, immunomodulatory, antinociceptive, pronociceptive, antibacterial, antifungal, antidiabetic, diuretic, and vasorelaxant effects. The results highlight the significant medicinal potential of
A. oleracea
while also identifying areas for further research, particularly regarding its toxicological impacts on humans and animals. This review aims to guide future studies on the health benefits and safety of this plant.
Article Highlights
Acmella oleracea
exhibits significant pain-relieving properties, interacting with pain receptors effectively.
The plant's extracts show strong antimicrobial effects, useful against various bacterial infections.
Acmella oleracea
demonstrates potent antioxidant and antifungal activities, promoting health and disease prevention.</description><subject>Acmella oleracea</subject><subject>Analgesics</subject><subject>Antiinfectives and antibacterials</subject><subject>Antimicrobial activity</subject><subject>Antioxidants</subject><subject>Applied and Technical Physics</subject><subject>Bacterial diseases</subject><subject>Chemistry/Food Science</subject><subject>Diabetes mellitus</subject><subject>Diuretics</subject><subject>Earth Sciences</subject><subject>Engineering</subject><subject>Environment</subject><subject>Flowers & plants</subject><subject>Free radicals</subject><subject>Fungicides</subject><subject>Health promotion</subject><subject>Immunomodulation</subject><subject>Infections</subject><subject>Insecticides</subject><subject>Laboratory animals</subject><subject>Literature reviews</subject><subject>Materials Science</subject><subject>Medicinal plants</subject><subject>Pain</subject><subject>Pain perception</subject><subject>Pharmacology</subject><subject>Phytochemicals</subject><subject>Plant extracts</subject><subject>Receptor mechanisms</subject><subject>Review</subject><subject>Taxonomy</subject><subject>Ulcers</subject><issn>3004-9261</issn><issn>2523-3963</issn><issn>3004-9261</issn><issn>2523-3971</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kE1LAzEQhoMoWGr_gKeA59V8bXbjrRS_oKAHPYc0nXQj2c2abCv9966toCdPMwzP-zI8CF1Sck0JqW6yYKJkBWGiIJKSuihP0IQTIgrFJD39s5-jWc5-RUohGJdcTVB-aUxqjY0hbrw1AZtujftmP0TbQHu4JNh5-MTR4bltIQSDY4BkLJhbbLCNbZ-ggS77HYxpE_bZ52_aDxkPzUj2sB28xX0coBu8CRfozJmQYfYzp-jt_u518Vgsnx-eFvNlYZkQQ0FdWcl1VXLF15YYR63gXDFiJWW8JNJxCyvgYKjgVJgaaletlOCslk5WivApujr29il-bCEP-j1u0_hh1pzUkioiVTVS7EjZFHNO4HSffGvSXlOiv_3qo189-tUHv7ocQ_wYyiPcbSD9Vv-T-gIJ4H66</recordid><startdate>20240730</startdate><enddate>20240730</enddate><creator>Aktar, Mst. Asma</creator><creator>Bhuia, Md. Shimul</creator><creator>Molla, Shamim</creator><creator>Chowdhury, Raihan</creator><creator>Sarkar, Chandan</creator><creator>Al Shahariar, Md</creator><creator>Roy, Pias</creator><creator>Reiner, Željko</creator><creator>Sharifi-Rad, Javad</creator><creator>Calina, Daniela</creator><creator>Shakil, Md. Abdul Kader</creator><creator>Islam, Muhammad Torequl</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7XB</scope><scope>88I</scope><scope>8FE</scope><scope>8FG</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>KB.</scope><scope>L6V</scope><scope>M2P</scope><scope>M7S</scope><scope>PATMY</scope><scope>PCBAR</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>Q9U</scope></search><sort><creationdate>20240730</creationdate><title>Pharmacological and phytochemical review of Acmella oleracea: a comprehensive analysis of its therapeutic potential</title><author>Aktar, Mst. Asma ; Bhuia, Md. Shimul ; Molla, Shamim ; Chowdhury, Raihan ; Sarkar, Chandan ; Al Shahariar, Md ; Roy, Pias ; Reiner, Željko ; Sharifi-Rad, Javad ; Calina, Daniela ; Shakil, Md. 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Asma</au><au>Bhuia, Md. Shimul</au><au>Molla, Shamim</au><au>Chowdhury, Raihan</au><au>Sarkar, Chandan</au><au>Al Shahariar, Md</au><au>Roy, Pias</au><au>Reiner, Željko</au><au>Sharifi-Rad, Javad</au><au>Calina, Daniela</au><au>Shakil, Md. Abdul Kader</au><au>Islam, Muhammad Torequl</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pharmacological and phytochemical review of Acmella oleracea: a comprehensive analysis of its therapeutic potential</atitle><jtitle>Discover Applied Sciences</jtitle><stitle>Discov Appl Sci</stitle><date>2024-07-30</date><risdate>2024</risdate><volume>6</volume><issue>8</issue><spage>412</spage><pages>412-</pages><artnum>412</artnum><issn>3004-9261</issn><issn>2523-3963</issn><eissn>3004-9261</eissn><eissn>2523-3971</eissn><abstract>Acmella oleracea
L. (Asteraceae), commonly known as the toothache plant, is a tropical herb with significant therapeutic potential. Traditionally, it has been used for its analgesic and sialagogue properties, and it is known for its distinctive yellow flower crest. This review addresses current gaps in the understanding of its pharmacological properties and aims to provide a comprehensive analysis of its therapeutic potential. A thorough literature review was conducted using databases such as Google Scholar, ScienceDirect, and PubMed/MedLine. The findings indicate that A
. oleracea
contains a variety of phytochemicals, including spilanthol, which exhibit diverse pharmacological activities such as antioxidant, anti-inflammatory, immunomodulatory, antinociceptive, pronociceptive, antibacterial, antifungal, antidiabetic, diuretic, and vasorelaxant effects. The results highlight the significant medicinal potential of
A. oleracea
while also identifying areas for further research, particularly regarding its toxicological impacts on humans and animals. This review aims to guide future studies on the health benefits and safety of this plant.
Article Highlights
Acmella oleracea
exhibits significant pain-relieving properties, interacting with pain receptors effectively.
The plant's extracts show strong antimicrobial effects, useful against various bacterial infections.
Acmella oleracea
demonstrates potent antioxidant and antifungal activities, promoting health and disease prevention.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><doi>10.1007/s42452-024-06108-5</doi><oa>free_for_read</oa></addata></record> |
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| ispartof | Discover Applied Sciences, 2024-07, Vol.6 (8), p.412, Article 412 |
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| subjects | Acmella oleracea Analgesics Antiinfectives and antibacterials Antimicrobial activity Antioxidants Applied and Technical Physics Bacterial diseases Chemistry/Food Science Diabetes mellitus Diuretics Earth Sciences Engineering Environment Flowers & plants Free radicals Fungicides Health promotion Immunomodulation Infections Insecticides Laboratory animals Literature reviews Materials Science Medicinal plants Pain Pain perception Pharmacology Phytochemicals Plant extracts Receptor mechanisms Review Taxonomy Ulcers |
| title | Pharmacological and phytochemical review of Acmella oleracea: a comprehensive analysis of its therapeutic potential |
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