Platinum Nanoparticles in Aqueous Solutions of a Chitosan–Vinylpyrrolidone Copolymer: Synthesis and Biological Activity

Grafted copolymers of chitosan–vinylpyrrolidone, water-soluble at a pH of 6.8–7.5, were obtained. A technique has been developed for obtaining an aggregatively stable system of platinum nanoparticles in copolymer solutions with an average size of ~4 nm. The thermophysical and structural characterist...

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Veröffentlicht in:	Applied biochemistry and microbiology 2024-08, Vol.60 (4), p.676-685
Hauptverfasser:	Zuev, D. N., Cherkasova, E. I., Apryatina, K. V., Zaitsev, S. D., Smirnova, L. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties antineoplastic activity Antitumor activity Antitumor agents Aqueous solutions Biochemistry Biocompatibility Biological activity Biomedical and Life Sciences Cell culture Chemical synthesis Chitosan Cisplatin composite polymers Composition effects Copolymers Effectiveness Graft copolymers Life Sciences Medical Microbiology Microbiology Nanoparticles Platinum Thermophysical properties Vinylpyrrolidone water solubility
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