Photoannealing of Microtissues Creates High‐Density Capillary Network Containing Living Matter in a Volumetric‐Independent Manner (Adv. Mater. 28/2024)

Tissue Engineering In article number 2308949 by Maik Schot, Jeroen Leijten, and co‐workers, engineered living tissues containing high density capillary networks are fabricated in a clinically scalable manner. This is achieved by photo‐annealing living microtissues, which are mass produced using in‐air microfluidics. The resulting microporous yet monolithic living tissues are directly perfusable and offer micrometer‐scale diffusive length regardless of tissue size, enabling unprecedented exchange rates for nutrients, waste products, and stimulating molecules to allow for the upscaling of living matter.