Key Role of Water in Copper‐ and Base‐free Sonogashira Coupling in Ethanol with [{Pd(μ‐OH)Cl(IPr)}2] as a Highly Effective Precatalyst

Aryl bromides and 4‐chlorotoluene as an example aryl chloride in the presence of N‐heterocyclic carbene (NHC) palladium hydroxo dimers of the type [{Pd(μ‐OH)Cl(NHC)}2] (where NHC=IPr, SIPr, IMes, SIMes) undergo an efficient and selective Sonogashira cross‐coupling with (hetero)arylacetylenes. The pr...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	ChemCatChem 2024-07, Vol.16 (13), p.n/a
Hauptverfasser:	Ostrowska, Sylwia, Rogalski, Szymon, Pietraszuk, Cezary
Format:	Artikel
Sprache:	eng
Schlagworte:	Aromatic compounds Bromides Chemical reactions Chlorotoluene copper- and base-free Sonogashira Cross coupling Ethanol Hydrogen chloride NHC complexes Oxidation Palladium reaction mechanism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!