Histological analysis of bone grafts fixed with ethyl‐cyanoacrylate and fixed with titanium screw: An experimental study on rats
Objectives The aim of this study was to evaluate, through qualitative and semi‐quantitative histological analysis, onlay autologous bone grafts fixed with ethyl‐cyanoacrylate adhesive and titanium screw, in order to verify whether the method of applying the adhesive would interfere with the graft in...
Gespeichert in:
| Veröffentlicht in: | Oral surgery 2024-08, Vol.17 (3), p.233-242 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 242 |
|---|---|
| container_issue | 3 |
| container_start_page | 233 |
| container_title | Oral surgery |
| container_volume | 17 |
| creator | Chandretti, Paula Carolina de Souza Santos, Rodrigo Falci Júlio, Isabelle Cristina Garcia Rocha, Ana Gabriela Carvalho Medeiros, Yuri de Lima Gollner, Ângela Maria Assis, Neuza Maria Souza Picorelli |
| description | Objectives
The aim of this study was to evaluate, through qualitative and semi‐quantitative histological analysis, onlay autologous bone grafts fixed with ethyl‐cyanoacrylate adhesive and titanium screw, in order to verify whether the method of applying the adhesive would interfere with the graft incorporation.
Materials and Methods
Fourteen rats underwent bone graft surgery: seven grafts were fixed with ethyl‐cyanoacrylate (SB group, n = 7) and seven grafts were fixed with titanium screws (TS group, n = 7). After 30 days, the grafts were histologically analysed for vitality, adhesive presence, tissue reaction with formation of osteoid matrix, bone resorption presence, capillaries formation, inflammatory infiltrate, fibroblastic proliferation, presence of osteoblasts, osteocytes and osteoclasts. The data were submitted to non‐parametric tests, Mann–Whitney, Fisher's Test, Wilcoxon and McNemar and to statistical analysis (p |
| doi_str_mv | 10.1111/ors.12884 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_3075591745</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3075591745</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1724-758a4428e433517ba7ce6cf615483a47e586e6cddc1babb86f1136a2d236d7433</originalsourceid><addsrcrecordid>eNp1kMtKAzEUhgdRsFYXvkHAlYtpJ5ncdFdErVAoeAF3IZPJtCnTSU0ytLMTn8Bn9EmMjogbz-YcDt9_Ln-SnMJsBGOMrfMjiDjHe8kAMoJShPnz_m_N4GFy5P0qyyiChA6St6nxwdZ2YZSsgWxk3Xnjga1AYRsNFk5WwYPK7HQJtiYsgQ7Lrv54fVedbKxUrqtl0FFY_oWCCbIx7Rp45fT2EkwaoHcb7cxaNyHu8aEtO2Ab4GTwx8lBJWuvT37yMHm6uX68mqaz-e3d1WSWKsgQThnhEmPENc5zAlkhmdJUVRQSzHOJmSacxkZZKljIouC0gjCnEpUopyWLomFy1s_dOPvSah_EyrYufuxFnjFCLiDDJFLnPaWc9d7pSmzi2dJ1Ambiy2IRLRbfFkd23LNbU-vuf1DM7x96xSeQjoDw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3075591745</pqid></control><display><type>article</type><title>Histological analysis of bone grafts fixed with ethyl‐cyanoacrylate and fixed with titanium screw: An experimental study on rats</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Chandretti, Paula Carolina de Souza ; Santos, Rodrigo Falci ; Júlio, Isabelle Cristina Garcia ; Rocha, Ana Gabriela Carvalho ; Medeiros, Yuri de Lima ; Gollner, Ângela Maria ; Assis, Neuza Maria Souza Picorelli</creator><creatorcontrib>Chandretti, Paula Carolina de Souza ; Santos, Rodrigo Falci ; Júlio, Isabelle Cristina Garcia ; Rocha, Ana Gabriela Carvalho ; Medeiros, Yuri de Lima ; Gollner, Ângela Maria ; Assis, Neuza Maria Souza Picorelli</creatorcontrib><description>Objectives
The aim of this study was to evaluate, through qualitative and semi‐quantitative histological analysis, onlay autologous bone grafts fixed with ethyl‐cyanoacrylate adhesive and titanium screw, in order to verify whether the method of applying the adhesive would interfere with the graft incorporation.
Materials and Methods
Fourteen rats underwent bone graft surgery: seven grafts were fixed with ethyl‐cyanoacrylate (SB group, n = 7) and seven grafts were fixed with titanium screws (TS group, n = 7). After 30 days, the grafts were histologically analysed for vitality, adhesive presence, tissue reaction with formation of osteoid matrix, bone resorption presence, capillaries formation, inflammatory infiltrate, fibroblastic proliferation, presence of osteoblasts, osteocytes and osteoclasts. The data were submitted to non‐parametric tests, Mann–Whitney, Fisher's Test, Wilcoxon and McNemar and to statistical analysis (p < 0.05).
Results
No significant differences were found in the qualitative evaluations. While findings of more osteocytes (p = 0.035) in the TS group in greater inflammation (p = 0.030) and more osteoclasts (p = 0.048) in the SB. Despite the fact that the titanium screw has presented bone neoformation with welding points, there was no complete incorporation and the adhesive affected the bone repair in a way that not even neoformation points could be seen in 30 days.
Conclusion
The method of applying the adhesive did not show an advantage according to the histological aspects studied, as there was the formation of a dead space at the interface of the SB group and the adhesive acted as a barrier.</description><identifier>ISSN: 1752-2471</identifier><identifier>EISSN: 1752-248X</identifier><identifier>DOI: 10.1111/ors.12884</identifier><language>eng</language><publisher>Edinburgh: Wiley Subscription Services, Inc</publisher><subject>Adhesives ; bone fixation ; bone graft ; Bone grafts ; Bone growth ; Bone healing ; Bone matrix ; Bone resorption ; Bone surgery ; Capillaries ; Inflammation ; Osteoclasts ; Osteocytes ; Osteoid ; Skin & tissue grafts ; Statistical analysis ; tissue adhesive ; Titanium</subject><ispartof>Oral surgery, 2024-08, Vol.17 (3), p.233-242</ispartof><rights>2024 British Association of Oral Surgeons and John Wiley & Sons Ltd.</rights><rights>Copyright © 2024 The British Association of Oral Surgeons and John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1724-758a4428e433517ba7ce6cf615483a47e586e6cddc1babb86f1136a2d236d7433</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fors.12884$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fors.12884$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids></links><search><creatorcontrib>Chandretti, Paula Carolina de Souza</creatorcontrib><creatorcontrib>Santos, Rodrigo Falci</creatorcontrib><creatorcontrib>Júlio, Isabelle Cristina Garcia</creatorcontrib><creatorcontrib>Rocha, Ana Gabriela Carvalho</creatorcontrib><creatorcontrib>Medeiros, Yuri de Lima</creatorcontrib><creatorcontrib>Gollner, Ângela Maria</creatorcontrib><creatorcontrib>Assis, Neuza Maria Souza Picorelli</creatorcontrib><title>Histological analysis of bone grafts fixed with ethyl‐cyanoacrylate and fixed with titanium screw: An experimental study on rats</title><title>Oral surgery</title><description>Objectives
The aim of this study was to evaluate, through qualitative and semi‐quantitative histological analysis, onlay autologous bone grafts fixed with ethyl‐cyanoacrylate adhesive and titanium screw, in order to verify whether the method of applying the adhesive would interfere with the graft incorporation.
Materials and Methods
Fourteen rats underwent bone graft surgery: seven grafts were fixed with ethyl‐cyanoacrylate (SB group, n = 7) and seven grafts were fixed with titanium screws (TS group, n = 7). After 30 days, the grafts were histologically analysed for vitality, adhesive presence, tissue reaction with formation of osteoid matrix, bone resorption presence, capillaries formation, inflammatory infiltrate, fibroblastic proliferation, presence of osteoblasts, osteocytes and osteoclasts. The data were submitted to non‐parametric tests, Mann–Whitney, Fisher's Test, Wilcoxon and McNemar and to statistical analysis (p < 0.05).
Results
No significant differences were found in the qualitative evaluations. While findings of more osteocytes (p = 0.035) in the TS group in greater inflammation (p = 0.030) and more osteoclasts (p = 0.048) in the SB. Despite the fact that the titanium screw has presented bone neoformation with welding points, there was no complete incorporation and the adhesive affected the bone repair in a way that not even neoformation points could be seen in 30 days.
Conclusion
The method of applying the adhesive did not show an advantage according to the histological aspects studied, as there was the formation of a dead space at the interface of the SB group and the adhesive acted as a barrier.</description><subject>Adhesives</subject><subject>bone fixation</subject><subject>bone graft</subject><subject>Bone grafts</subject><subject>Bone growth</subject><subject>Bone healing</subject><subject>Bone matrix</subject><subject>Bone resorption</subject><subject>Bone surgery</subject><subject>Capillaries</subject><subject>Inflammation</subject><subject>Osteoclasts</subject><subject>Osteocytes</subject><subject>Osteoid</subject><subject>Skin & tissue grafts</subject><subject>Statistical analysis</subject><subject>tissue adhesive</subject><subject>Titanium</subject><issn>1752-2471</issn><issn>1752-248X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp1kMtKAzEUhgdRsFYXvkHAlYtpJ5ncdFdErVAoeAF3IZPJtCnTSU0ytLMTn8Bn9EmMjogbz-YcDt9_Ln-SnMJsBGOMrfMjiDjHe8kAMoJShPnz_m_N4GFy5P0qyyiChA6St6nxwdZ2YZSsgWxk3Xnjga1AYRsNFk5WwYPK7HQJtiYsgQ7Lrv54fVedbKxUrqtl0FFY_oWCCbIx7Rp45fT2EkwaoHcb7cxaNyHu8aEtO2Ab4GTwx8lBJWuvT37yMHm6uX68mqaz-e3d1WSWKsgQThnhEmPENc5zAlkhmdJUVRQSzHOJmSacxkZZKljIouC0gjCnEpUopyWLomFy1s_dOPvSah_EyrYufuxFnjFCLiDDJFLnPaWc9d7pSmzi2dJ1Ambiy2IRLRbfFkd23LNbU-vuf1DM7x96xSeQjoDw</recordid><startdate>202408</startdate><enddate>202408</enddate><creator>Chandretti, Paula Carolina de Souza</creator><creator>Santos, Rodrigo Falci</creator><creator>Júlio, Isabelle Cristina Garcia</creator><creator>Rocha, Ana Gabriela Carvalho</creator><creator>Medeiros, Yuri de Lima</creator><creator>Gollner, Ângela Maria</creator><creator>Assis, Neuza Maria Souza Picorelli</creator><general>Wiley Subscription Services, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope></search><sort><creationdate>202408</creationdate><title>Histological analysis of bone grafts fixed with ethyl‐cyanoacrylate and fixed with titanium screw: An experimental study on rats</title><author>Chandretti, Paula Carolina de Souza ; Santos, Rodrigo Falci ; Júlio, Isabelle Cristina Garcia ; Rocha, Ana Gabriela Carvalho ; Medeiros, Yuri de Lima ; Gollner, Ângela Maria ; Assis, Neuza Maria Souza Picorelli</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1724-758a4428e433517ba7ce6cf615483a47e586e6cddc1babb86f1136a2d236d7433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adhesives</topic><topic>bone fixation</topic><topic>bone graft</topic><topic>Bone grafts</topic><topic>Bone growth</topic><topic>Bone healing</topic><topic>Bone matrix</topic><topic>Bone resorption</topic><topic>Bone surgery</topic><topic>Capillaries</topic><topic>Inflammation</topic><topic>Osteoclasts</topic><topic>Osteocytes</topic><topic>Osteoid</topic><topic>Skin & tissue grafts</topic><topic>Statistical analysis</topic><topic>tissue adhesive</topic><topic>Titanium</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chandretti, Paula Carolina de Souza</creatorcontrib><creatorcontrib>Santos, Rodrigo Falci</creatorcontrib><creatorcontrib>Júlio, Isabelle Cristina Garcia</creatorcontrib><creatorcontrib>Rocha, Ana Gabriela Carvalho</creatorcontrib><creatorcontrib>Medeiros, Yuri de Lima</creatorcontrib><creatorcontrib>Gollner, Ângela Maria</creatorcontrib><creatorcontrib>Assis, Neuza Maria Souza Picorelli</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>Oral surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chandretti, Paula Carolina de Souza</au><au>Santos, Rodrigo Falci</au><au>Júlio, Isabelle Cristina Garcia</au><au>Rocha, Ana Gabriela Carvalho</au><au>Medeiros, Yuri de Lima</au><au>Gollner, Ângela Maria</au><au>Assis, Neuza Maria Souza Picorelli</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Histological analysis of bone grafts fixed with ethyl‐cyanoacrylate and fixed with titanium screw: An experimental study on rats</atitle><jtitle>Oral surgery</jtitle><date>2024-08</date><risdate>2024</risdate><volume>17</volume><issue>3</issue><spage>233</spage><epage>242</epage><pages>233-242</pages><issn>1752-2471</issn><eissn>1752-248X</eissn><abstract>Objectives
The aim of this study was to evaluate, through qualitative and semi‐quantitative histological analysis, onlay autologous bone grafts fixed with ethyl‐cyanoacrylate adhesive and titanium screw, in order to verify whether the method of applying the adhesive would interfere with the graft incorporation.
Materials and Methods
Fourteen rats underwent bone graft surgery: seven grafts were fixed with ethyl‐cyanoacrylate (SB group, n = 7) and seven grafts were fixed with titanium screws (TS group, n = 7). After 30 days, the grafts were histologically analysed for vitality, adhesive presence, tissue reaction with formation of osteoid matrix, bone resorption presence, capillaries formation, inflammatory infiltrate, fibroblastic proliferation, presence of osteoblasts, osteocytes and osteoclasts. The data were submitted to non‐parametric tests, Mann–Whitney, Fisher's Test, Wilcoxon and McNemar and to statistical analysis (p < 0.05).
Results
No significant differences were found in the qualitative evaluations. While findings of more osteocytes (p = 0.035) in the TS group in greater inflammation (p = 0.030) and more osteoclasts (p = 0.048) in the SB. Despite the fact that the titanium screw has presented bone neoformation with welding points, there was no complete incorporation and the adhesive affected the bone repair in a way that not even neoformation points could be seen in 30 days.
Conclusion
The method of applying the adhesive did not show an advantage according to the histological aspects studied, as there was the formation of a dead space at the interface of the SB group and the adhesive acted as a barrier.</abstract><cop>Edinburgh</cop><pub>Wiley Subscription Services, Inc</pub><doi>10.1111/ors.12884</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1752-2471 |
| ispartof | Oral surgery, 2024-08, Vol.17 (3), p.233-242 |
| issn | 1752-2471 1752-248X |
| language | eng |
| recordid | cdi_proquest_journals_3075591745 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Adhesives bone fixation bone graft Bone grafts Bone growth Bone healing Bone matrix Bone resorption Bone surgery Capillaries Inflammation Osteoclasts Osteocytes Osteoid Skin & tissue grafts Statistical analysis tissue adhesive Titanium |
| title | Histological analysis of bone grafts fixed with ethyl‐cyanoacrylate and fixed with titanium screw: An experimental study on rats |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T19%3A58%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Histological%20analysis%20of%20bone%20grafts%20fixed%20with%20ethyl%E2%80%90cyanoacrylate%20and%20fixed%20with%20titanium%20screw:%20An%20experimental%20study%20on%20rats&rft.jtitle=Oral%20surgery&rft.au=Chandretti,%20Paula%20Carolina%20de%20Souza&rft.date=2024-08&rft.volume=17&rft.issue=3&rft.spage=233&rft.epage=242&rft.pages=233-242&rft.issn=1752-2471&rft.eissn=1752-248X&rft_id=info:doi/10.1111/ors.12884&rft_dat=%3Cproquest_cross%3E3075591745%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3075591745&rft_id=info:pmid/&rfr_iscdi=true |