Chemical Synthesis of a Key Precursor Relevant to the Tetrasaccharide Repeating Unit from Treponema medium ATCC 700293

Comprehensive Summary Treponema is a Gram‐negative anaerobic bacterium, among which the pathogenic Treponema can cause various diseases, such as venereal syphilis (Treponema pallidum), yaws (Treponema carateum), and oral diseases (Treponema denticola and Treponema medium). Although different from co...

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Veröffentlicht in:	Chinese journal of chemistry 2024-07, Vol.42 (14), p.1615-1622
Hauptverfasser:	Sun, Wenbin, Tian, Guangzong, Ding, Meiru, Qin, Chunjun, Zou, Xiaopeng, Hu, Jing, Yin, Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Aspartic acid Bacteria Chemical synthesis Disaccharides Efficiency Glycosylation Hydroxyl groups Lipopolysaccharides Neighboring‐group effects Oligosaccharides Ornithine Polysaccharides Precursors Protecting group Protecting groups Regioselectivity Sexually transmitted diseases STD Stereospecificity Syphilis Tetrasaccharide precursor Total synthesis Treponema Treponema medium ATCC 700293 Vaccine development Yaws
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