An Indocyanine Green‐Based Nanoprobe for In Vivo Detection of Cellular Senescence

There is an urgent need to improve conventional cancer‐treatments by preventing detrimental side effects, cancer recurrence and metastases. Recent studies have shown that presence of senescent cells in tissues treated with chemo‐ or radiotherapy can be used to predict the effectiveness of cancer tre...

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Veröffentlicht in:	Angewandte Chemie 2024-06, Vol.136 (25), p.n/a
Hauptverfasser:	Baker, Andrew G., Hartono, Muhamad, Ou, Hui‐Ling, Popov, Andrea Bistrović, Brown, Emma L., Joseph, James, Golinska, Monika, González‐Gualda, Estela, Macias, David, Ge, Jianfeng, Denholm, Mary, Morsli, Samir, Sanghera, Chandan, Else, Thomas R., Greer, Heather F., Vernet, Aude, Bohndiek, Sarah E., Muñoz‐Espín, Daniel, Fruk, Ljiljana
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Cancer Cancer therapies Cellular senescence Chemotherapy Development strategies endocytosis ICG nanoprobe In vivo methods and tests Lysosomes Manufacturing industry Metastases Photoacoustic effect photoacoustic tomography (PAT) Radiation therapy Self-assembly Senescence Side effects Solid tumors Spectral signatures
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