A Modular Microfluidic Organoid Platform Using LEGO‐Like Bricks (Adv. Healthcare Mater. 13/2024)

A Modular Microfluidic Organoid Platform Using LEGO‐Like Bricks (Adv. Healthcare Mater. 13/2024)

Modular Bioreactor for Organoids In article 2303444, Stefan Giselbrecht and co‐workers present a modular bioreactor platform for organoids based on a Lock‐and‐Play concept. Reversibly sealed cell culture bricks for dynamic culture of embryonic stem cell‐derived thyroid follicles are coupled with a m...

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Veröffentlicht in:Advanced healthcare materials 2024-05, Vol.13 (13), p.n/a
Hauptverfasser: Carvalho, Daniel J., Kip, Anna M., Tegel, Andreas, Stich, Matthias, Krause, Christian, Romitti, Mírian, Branca, Carlotta, Verhoeven, Bart, Costagliola, Sabine, Moroni, Lorenzo, Giselbrecht, Stefan
Format: Artikel
Sprache:eng
Schlagworte:
Bioreactors
Bricks
Cell culture
Circuit boards
Embryo cells
Fluidic circuits
Follicles
Microfluidics
Organoids
Stem cells
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Zusammenfassung:Modular Bioreactor for Organoids In article 2303444, Stefan Giselbrecht and co‐workers present a modular bioreactor platform for organoids based on a Lock‐and‐Play concept. Reversibly sealed cell culture bricks for dynamic culture of embryonic stem cell‐derived thyroid follicles are coupled with a modular, tubeless fluidic circuit board. This novel system addresses the urgent need for flexible, easy‐to‐use platforms, capable of synergistically combining organoid technology with advanced microfluidics.
ISSN:2192-2640
2192-2659
DOI:10.1002/adhm.202470086