A Rare and Intriguing Case Report of Metaplastic Breast Carcinoma

Metaplastic breast carcinoma (MBC) is a rare and aggressive subtype of breast cancer characterized by the presence of both epithelial and mesenchymal components within the tumor. Its clinical and radiological appearance is comparable to other types of breast cancer, but it grows rapidly. The diagnos...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2024-03, Vol.16 (3), p.e56619
Hauptverfasser: Kani, Vallal, Chander, Vimal, Sonti, Sulochana, Manian, Sridevi, Vasudevan, Sudha, Esakki, Muthuvel, Grace Priyadarshini, Sarah, Rajendran, Karthika
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue 3
container_start_page e56619
container_title Curēus (Palo Alto, CA)
container_volume 16
creator Kani, Vallal
Chander, Vimal
Sonti, Sulochana
Manian, Sridevi
Vasudevan, Sudha
Esakki, Muthuvel
Grace Priyadarshini, Sarah
Rajendran, Karthika
description Metaplastic breast carcinoma (MBC) is a rare and aggressive subtype of breast cancer characterized by the presence of both epithelial and mesenchymal components within the tumor. Its clinical and radiological appearance is comparable to other types of breast cancer, but it grows rapidly. The diagnosis of metaplastic carcinoma is largely based on the epithelial origin of the cells confirmed by immunohistochemistry (IHC). Compared to invasive ductal carcinoma, metaplastic carcinoma has a worse overall survival rate. Any patient with a rapidly growing breast mass should be assessed with suspicion of sarcomatoid or metaplastic malignant neoplasm. We report this case due to its rarity and the complex nature of the disease.
doi_str_mv 10.7759/cureus.56619
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_3049794061</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3049794061</sourcerecordid><originalsourceid>FETCH-LOGICAL-c211t-fc978f74c69dbf762ffb49aab14c32b0da31a6c18fee3e4d6ab49ecea49255dc3</originalsourceid><addsrcrecordid>eNpNkMFLwzAUxoMobszdPEvAq51JkybNcY6pg4kw9Bxe05fRsbU1aQ_-91Y3xdP74P34PvgRcs3ZTOvM3Ls-YB9nmVLcnJFxylWe5DyX5__yiExj3DHGONMp0-ySjESupBJajMl8TjcQkEJd0lXdhWrbV_WWLiAi3WDbhI42nr5gB-0eYlc5-hBwCAMRXFU3B7giFx72EaenOyHvj8u3xXOyfn1aLebrxKWcd4l3RudeS6dMWXitUu8LaQAKLp1IC1aC4KAczz2iQFkqGN7oEKRJs6x0YkJuj71taD56jJ3dNX2oh0krmDTaSKb4QN0dKReaGAN624bqAOHTcma_ldmjMvujbMBvTqV9ccDyD_4VJL4AtsZn5g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3049794061</pqid></control><display><type>article</type><title>A Rare and Intriguing Case Report of Metaplastic Breast Carcinoma</title><source>PubMed Central</source><source>PubMed Central Open Access</source><creator>Kani, Vallal ; Chander, Vimal ; Sonti, Sulochana ; Manian, Sridevi ; Vasudevan, Sudha ; Esakki, Muthuvel ; Grace Priyadarshini, Sarah ; Rajendran, Karthika</creator><creatorcontrib>Kani, Vallal ; Chander, Vimal ; Sonti, Sulochana ; Manian, Sridevi ; Vasudevan, Sudha ; Esakki, Muthuvel ; Grace Priyadarshini, Sarah ; Rajendran, Karthika</creatorcontrib><description>Metaplastic breast carcinoma (MBC) is a rare and aggressive subtype of breast cancer characterized by the presence of both epithelial and mesenchymal components within the tumor. Its clinical and radiological appearance is comparable to other types of breast cancer, but it grows rapidly. The diagnosis of metaplastic carcinoma is largely based on the epithelial origin of the cells confirmed by immunohistochemistry (IHC). Compared to invasive ductal carcinoma, metaplastic carcinoma has a worse overall survival rate. Any patient with a rapidly growing breast mass should be assessed with suspicion of sarcomatoid or metaplastic malignant neoplasm. We report this case due to its rarity and the complex nature of the disease.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.56619</identifier><identifier>PMID: 38646373</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Biopsy ; Body fat ; Breast cancer ; Cancer therapies ; Case reports ; Cellular biology ; Chemotherapy ; Cytokeratin ; Epidermal growth factor ; Estrogens ; Foreign bodies ; Hyperplasia ; Mastectomy ; Medical prognosis ; Microscopy ; Radiation therapy ; Tumors</subject><ispartof>Curēus (Palo Alto, CA), 2024-03, Vol.16 (3), p.e56619</ispartof><rights>Copyright © 2024, Kani et al.</rights><rights>Copyright © 2024, Kani et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c211t-fc978f74c69dbf762ffb49aab14c32b0da31a6c18fee3e4d6ab49ecea49255dc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38646373$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kani, Vallal</creatorcontrib><creatorcontrib>Chander, Vimal</creatorcontrib><creatorcontrib>Sonti, Sulochana</creatorcontrib><creatorcontrib>Manian, Sridevi</creatorcontrib><creatorcontrib>Vasudevan, Sudha</creatorcontrib><creatorcontrib>Esakki, Muthuvel</creatorcontrib><creatorcontrib>Grace Priyadarshini, Sarah</creatorcontrib><creatorcontrib>Rajendran, Karthika</creatorcontrib><title>A Rare and Intriguing Case Report of Metaplastic Breast Carcinoma</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Metaplastic breast carcinoma (MBC) is a rare and aggressive subtype of breast cancer characterized by the presence of both epithelial and mesenchymal components within the tumor. Its clinical and radiological appearance is comparable to other types of breast cancer, but it grows rapidly. The diagnosis of metaplastic carcinoma is largely based on the epithelial origin of the cells confirmed by immunohistochemistry (IHC). Compared to invasive ductal carcinoma, metaplastic carcinoma has a worse overall survival rate. Any patient with a rapidly growing breast mass should be assessed with suspicion of sarcomatoid or metaplastic malignant neoplasm. We report this case due to its rarity and the complex nature of the disease.</description><subject>Biopsy</subject><subject>Body fat</subject><subject>Breast cancer</subject><subject>Cancer therapies</subject><subject>Case reports</subject><subject>Cellular biology</subject><subject>Chemotherapy</subject><subject>Cytokeratin</subject><subject>Epidermal growth factor</subject><subject>Estrogens</subject><subject>Foreign bodies</subject><subject>Hyperplasia</subject><subject>Mastectomy</subject><subject>Medical prognosis</subject><subject>Microscopy</subject><subject>Radiation therapy</subject><subject>Tumors</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpNkMFLwzAUxoMobszdPEvAq51JkybNcY6pg4kw9Bxe05fRsbU1aQ_-91Y3xdP74P34PvgRcs3ZTOvM3Ls-YB9nmVLcnJFxylWe5DyX5__yiExj3DHGONMp0-ySjESupBJajMl8TjcQkEJd0lXdhWrbV_WWLiAi3WDbhI42nr5gB-0eYlc5-hBwCAMRXFU3B7giFx72EaenOyHvj8u3xXOyfn1aLebrxKWcd4l3RudeS6dMWXitUu8LaQAKLp1IC1aC4KAczz2iQFkqGN7oEKRJs6x0YkJuj71taD56jJ3dNX2oh0krmDTaSKb4QN0dKReaGAN624bqAOHTcma_ldmjMvujbMBvTqV9ccDyD_4VJL4AtsZn5g</recordid><startdate>20240321</startdate><enddate>20240321</enddate><creator>Kani, Vallal</creator><creator>Chander, Vimal</creator><creator>Sonti, Sulochana</creator><creator>Manian, Sridevi</creator><creator>Vasudevan, Sudha</creator><creator>Esakki, Muthuvel</creator><creator>Grace Priyadarshini, Sarah</creator><creator>Rajendran, Karthika</creator><general>Cureus Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20240321</creationdate><title>A Rare and Intriguing Case Report of Metaplastic Breast Carcinoma</title><author>Kani, Vallal ; Chander, Vimal ; Sonti, Sulochana ; Manian, Sridevi ; Vasudevan, Sudha ; Esakki, Muthuvel ; Grace Priyadarshini, Sarah ; Rajendran, Karthika</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c211t-fc978f74c69dbf762ffb49aab14c32b0da31a6c18fee3e4d6ab49ecea49255dc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Biopsy</topic><topic>Body fat</topic><topic>Breast cancer</topic><topic>Cancer therapies</topic><topic>Case reports</topic><topic>Cellular biology</topic><topic>Chemotherapy</topic><topic>Cytokeratin</topic><topic>Epidermal growth factor</topic><topic>Estrogens</topic><topic>Foreign bodies</topic><topic>Hyperplasia</topic><topic>Mastectomy</topic><topic>Medical prognosis</topic><topic>Microscopy</topic><topic>Radiation therapy</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kani, Vallal</creatorcontrib><creatorcontrib>Chander, Vimal</creatorcontrib><creatorcontrib>Sonti, Sulochana</creatorcontrib><creatorcontrib>Manian, Sridevi</creatorcontrib><creatorcontrib>Vasudevan, Sudha</creatorcontrib><creatorcontrib>Esakki, Muthuvel</creatorcontrib><creatorcontrib>Grace Priyadarshini, Sarah</creatorcontrib><creatorcontrib>Rajendran, Karthika</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kani, Vallal</au><au>Chander, Vimal</au><au>Sonti, Sulochana</au><au>Manian, Sridevi</au><au>Vasudevan, Sudha</au><au>Esakki, Muthuvel</au><au>Grace Priyadarshini, Sarah</au><au>Rajendran, Karthika</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Rare and Intriguing Case Report of Metaplastic Breast Carcinoma</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2024-03-21</date><risdate>2024</risdate><volume>16</volume><issue>3</issue><spage>e56619</spage><pages>e56619-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Metaplastic breast carcinoma (MBC) is a rare and aggressive subtype of breast cancer characterized by the presence of both epithelial and mesenchymal components within the tumor. Its clinical and radiological appearance is comparable to other types of breast cancer, but it grows rapidly. The diagnosis of metaplastic carcinoma is largely based on the epithelial origin of the cells confirmed by immunohistochemistry (IHC). Compared to invasive ductal carcinoma, metaplastic carcinoma has a worse overall survival rate. Any patient with a rapidly growing breast mass should be assessed with suspicion of sarcomatoid or metaplastic malignant neoplasm. We report this case due to its rarity and the complex nature of the disease.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>38646373</pmid><doi>10.7759/cureus.56619</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2168-8184
ispartof Curēus (Palo Alto, CA), 2024-03, Vol.16 (3), p.e56619
issn 2168-8184
2168-8184
language eng
recordid cdi_proquest_journals_3049794061
source PubMed Central; PubMed Central Open Access
subjects Biopsy
Body fat
Breast cancer
Cancer therapies
Case reports
Cellular biology
Chemotherapy
Cytokeratin
Epidermal growth factor
Estrogens
Foreign bodies
Hyperplasia
Mastectomy
Medical prognosis
Microscopy
Radiation therapy
Tumors
title A Rare and Intriguing Case Report of Metaplastic Breast Carcinoma
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T13%3A42%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Rare%20and%20Intriguing%20Case%20Report%20of%20Metaplastic%20Breast%20Carcinoma&rft.jtitle=Cur%C4%93us%20(Palo%20Alto,%20CA)&rft.au=Kani,%20Vallal&rft.date=2024-03-21&rft.volume=16&rft.issue=3&rft.spage=e56619&rft.pages=e56619-&rft.issn=2168-8184&rft.eissn=2168-8184&rft_id=info:doi/10.7759/cureus.56619&rft_dat=%3Cproquest_cross%3E3049794061%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3049794061&rft_id=info:pmid/38646373&rfr_iscdi=true