Nickel-free cross-electrophile coupling of unactivated alkyl bromides with thiosulfonates and sulfinyl sulfones

An unusual zinc-promoted reductive coupling between alkyl bromides and thiosulfonates under nickel-free conditions is described. This practical strategy provides an attractive approach to access a series of structure-varied sulfides, which are privileged motifs in ligands, pharmaceuticals and materi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Organic Chemistry Frontiers 2024-04, Vol.11 (9), p.2518-2527
Hauptverfasser:	Fan, Qiujin, Zhao, Yanchuang, Liang, Jintao, Zhang, Yan, Xu, Yuenian, Zhang, Qingqing, Zhu, Hua, Jiang, Min, Shao, Xinxin
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological activity Bromides Chemical synthesis Coupling Nickel Sulfones Zinc
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!