Clinical Study of Preoperative Prehabilitation Synchronized Neoadjuvant Chemotherapy for Gastric Cancer Patients
Background. To investigate the effectiveness of prehabilitation in improving physical and nutritional status in patients undergoing gastric cancer resection. Methods. A total of 136 locally advanced gastric cancer patients who planned to undergo neoadjuvant chemotherapy (NAC) plus transabdominal rad...
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| Veröffentlicht in: | European journal of cancer care 2024-03, Vol.2024, p.1-9 |
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| creator | Li, Li Liu, Jiaxin Zhang, Yong Wang, Jing Li, Shoumiao |
| description | Background. To investigate the effectiveness of prehabilitation in improving physical and nutritional status in patients undergoing gastric cancer resection. Methods. A total of 136 locally advanced gastric cancer patients who planned to undergo neoadjuvant chemotherapy (NAC) plus transabdominal radical surgery were involved. All participants were divided into the prehabilitation group and the control group using the odd-even method, with 68 cases in each group. Intervention consisted of preoperative exercise and nutrition optimization. Participants were adults awaiting elective gastric resection for cancer. The primary outcomes were changes in functional ability and nutritional status, as measured by relative changes in 6 minute walking distance (6MWD) and scores on the albumin and prealbumin. Preoperative (end of the prehabilitation period) and postoperative (from 4 to 6 weeks after surgery) data were compared between the two groups. Results. All 136 patients were randomized in this study. Compared with the control group, the prehabilitation group exhibited improved functional capacity both before surgery (6MWD change) and after surgery. Furthermore, it demonstrated significantly higher levels of albumin and prealbumin before and after surgery than the control group. Conclusion. Prehabilitation in gastric cancer patients can improve preoperative functional capacity and nutritional status. Maintaining a patient’s physical function and nutritional status may have a significant impact on the continuity of cancer care. |
| doi_str_mv | 10.1155/2024/9494994 |
| format | Article |
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To investigate the effectiveness of prehabilitation in improving physical and nutritional status in patients undergoing gastric cancer resection. Methods. A total of 136 locally advanced gastric cancer patients who planned to undergo neoadjuvant chemotherapy (NAC) plus transabdominal radical surgery were involved. All participants were divided into the prehabilitation group and the control group using the odd-even method, with 68 cases in each group. Intervention consisted of preoperative exercise and nutrition optimization. Participants were adults awaiting elective gastric resection for cancer. The primary outcomes were changes in functional ability and nutritional status, as measured by relative changes in 6 minute walking distance (6MWD) and scores on the albumin and prealbumin. Preoperative (end of the prehabilitation period) and postoperative (from 4 to 6 weeks after surgery) data were compared between the two groups. Results. All 136 patients were randomized in this study. Compared with the control group, the prehabilitation group exhibited improved functional capacity both before surgery (6MWD change) and after surgery. Furthermore, it demonstrated significantly higher levels of albumin and prealbumin before and after surgery than the control group. Conclusion. Prehabilitation in gastric cancer patients can improve preoperative functional capacity and nutritional status. Maintaining a patient’s physical function and nutritional status may have a significant impact on the continuity of cancer care.</description><identifier>ISSN: 0961-5423</identifier><identifier>EISSN: 1365-2354</identifier><identifier>DOI: 10.1155/2024/9494994</identifier><language>eng</language><publisher>Oxford: Hindawi</publisher><subject>Abdomen ; Adjuvant treatment ; Aerobics ; Albumin ; Albumins ; Angina pectoris ; Cancer ; Cancer patients ; Cancer therapies ; Care and treatment ; Chemotherapy ; Clinical trials ; Consent ; Exercise ; Exercise therapy ; Fitness training programs ; Gastric cancer ; Gastrointestinal surgery ; Hospitals ; Intervention ; Malnutrition ; Medical prognosis ; Mortality ; Nurse practitioners ; Nutrition ; Nutritional status ; Oncology, Experimental ; Patients ; Physical fitness ; Quality of life ; Recovery (Medical) ; Rehabilitation ; Stomach cancer ; Surgery ; Tumors</subject><ispartof>European journal of cancer care, 2024-03, Vol.2024, p.1-9</ispartof><rights>Copyright © 2024 Li Li et al.</rights><rights>COPYRIGHT 2024 John Wiley & Sons, Inc.</rights><rights>Copyright © 2024 Li Li et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c361t-d7b267c5148a5e83a59585f693563013aace79ed1c0f5d75fe070aa7358aea43</cites><orcidid>0009-0007-2622-1839 ; 0000-0002-9814-519X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/3020594019/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3020594019?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,21367,27901,27902,33721,43781,74045</link.rule.ids></links><search><contributor>Kalhori, Mohammad Reza</contributor><creatorcontrib>Li, Li</creatorcontrib><creatorcontrib>Liu, Jiaxin</creatorcontrib><creatorcontrib>Zhang, Yong</creatorcontrib><creatorcontrib>Wang, Jing</creatorcontrib><creatorcontrib>Li, Shoumiao</creatorcontrib><title>Clinical Study of Preoperative Prehabilitation Synchronized Neoadjuvant Chemotherapy for Gastric Cancer Patients</title><title>European journal of cancer care</title><description>Background. To investigate the effectiveness of prehabilitation in improving physical and nutritional status in patients undergoing gastric cancer resection. Methods. A total of 136 locally advanced gastric cancer patients who planned to undergo neoadjuvant chemotherapy (NAC) plus transabdominal radical surgery were involved. All participants were divided into the prehabilitation group and the control group using the odd-even method, with 68 cases in each group. Intervention consisted of preoperative exercise and nutrition optimization. Participants were adults awaiting elective gastric resection for cancer. The primary outcomes were changes in functional ability and nutritional status, as measured by relative changes in 6 minute walking distance (6MWD) and scores on the albumin and prealbumin. Preoperative (end of the prehabilitation period) and postoperative (from 4 to 6 weeks after surgery) data were compared between the two groups. Results. All 136 patients were randomized in this study. Compared with the control group, the prehabilitation group exhibited improved functional capacity both before surgery (6MWD change) and after surgery. Furthermore, it demonstrated significantly higher levels of albumin and prealbumin before and after surgery than the control group. Conclusion. Prehabilitation in gastric cancer patients can improve preoperative functional capacity and nutritional status. Maintaining a patient’s physical function and nutritional status may have a significant impact on the continuity of cancer care.</description><subject>Abdomen</subject><subject>Adjuvant treatment</subject><subject>Aerobics</subject><subject>Albumin</subject><subject>Albumins</subject><subject>Angina pectoris</subject><subject>Cancer</subject><subject>Cancer patients</subject><subject>Cancer therapies</subject><subject>Care and treatment</subject><subject>Chemotherapy</subject><subject>Clinical trials</subject><subject>Consent</subject><subject>Exercise</subject><subject>Exercise therapy</subject><subject>Fitness training programs</subject><subject>Gastric cancer</subject><subject>Gastrointestinal surgery</subject><subject>Hospitals</subject><subject>Intervention</subject><subject>Malnutrition</subject><subject>Medical prognosis</subject><subject>Mortality</subject><subject>Nurse practitioners</subject><subject>Nutrition</subject><subject>Nutritional status</subject><subject>Oncology, Experimental</subject><subject>Patients</subject><subject>Physical fitness</subject><subject>Quality of life</subject><subject>Recovery (Medical)</subject><subject>Rehabilitation</subject><subject>Stomach cancer</subject><subject>Surgery</subject><subject>Tumors</subject><issn>0961-5423</issn><issn>1365-2354</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kdFrFDEQxoMoeFbf_AMCPuq2ySbZ3TyWRatQtNC-h2l24ubYS9YkVzn_enNcQQpS5mH4ht83M_AR8p6zc86VumhZKy-0rKXlC7LholNNK5R8STZMd7xRshWvyZuct4xxwbXckHVcfPAWFnpb9tOBRkdvEsYVExT_gEcxw71ffKk6Bnp7CHZOMfg_ONHvGGHa7h8gFDrOuItlrr71QF1M9ApySd7SEYLFRG-qH0PJb8krB0vGd4_9jNx9-Xw3fm2uf1x9Gy-vGys6Xpqpv2-73iouB1A4CFBaDcp1WqhO1OcBLPYaJ26ZU1OvHLKeAfRCDYAgxRn5cFq7pvhrj7mYbdynUC8awVqmtGRc_6N-woLGBxdLArvz2ZrLfhhaMaiur9T5f6haE-68jQGdr_Mnhk8ng00x54TOrMnvIB0MZ-aYlDkmZR6TqvjHEz77MMFv_zz9Fxocktg</recordid><startdate>20240321</startdate><enddate>20240321</enddate><creator>Li, Li</creator><creator>Liu, Jiaxin</creator><creator>Zhang, Yong</creator><creator>Wang, Jing</creator><creator>Li, Shoumiao</creator><general>Hindawi</general><general>John Wiley & Sons, Inc</general><general>Hindawi Limited</general><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ASE</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FPQ</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K6X</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><orcidid>https://orcid.org/0009-0007-2622-1839</orcidid><orcidid>https://orcid.org/0000-0002-9814-519X</orcidid></search><sort><creationdate>20240321</creationdate><title>Clinical Study of Preoperative Prehabilitation Synchronized Neoadjuvant Chemotherapy for Gastric Cancer Patients</title><author>Li, Li ; Liu, Jiaxin ; Zhang, Yong ; Wang, Jing ; Li, Shoumiao</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c361t-d7b267c5148a5e83a59585f693563013aace79ed1c0f5d75fe070aa7358aea43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Abdomen</topic><topic>Adjuvant treatment</topic><topic>Aerobics</topic><topic>Albumin</topic><topic>Albumins</topic><topic>Angina pectoris</topic><topic>Cancer</topic><topic>Cancer patients</topic><topic>Cancer therapies</topic><topic>Care and treatment</topic><topic>Chemotherapy</topic><topic>Clinical trials</topic><topic>Consent</topic><topic>Exercise</topic><topic>Exercise therapy</topic><topic>Fitness training programs</topic><topic>Gastric cancer</topic><topic>Gastrointestinal surgery</topic><topic>Hospitals</topic><topic>Intervention</topic><topic>Malnutrition</topic><topic>Medical prognosis</topic><topic>Mortality</topic><topic>Nurse practitioners</topic><topic>Nutrition</topic><topic>Nutritional status</topic><topic>Oncology, Experimental</topic><topic>Patients</topic><topic>Physical fitness</topic><topic>Quality of life</topic><topic>Recovery (Medical)</topic><topic>Rehabilitation</topic><topic>Stomach cancer</topic><topic>Surgery</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Li</creatorcontrib><creatorcontrib>Liu, Jiaxin</creatorcontrib><creatorcontrib>Zhang, Yong</creatorcontrib><creatorcontrib>Wang, Jing</creatorcontrib><creatorcontrib>Li, Shoumiao</creatorcontrib><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Index</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><jtitle>European journal of cancer care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Li</au><au>Liu, Jiaxin</au><au>Zhang, Yong</au><au>Wang, Jing</au><au>Li, Shoumiao</au><au>Kalhori, Mohammad Reza</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical Study of Preoperative Prehabilitation Synchronized Neoadjuvant Chemotherapy for Gastric Cancer Patients</atitle><jtitle>European journal of cancer care</jtitle><date>2024-03-21</date><risdate>2024</risdate><volume>2024</volume><spage>1</spage><epage>9</epage><pages>1-9</pages><issn>0961-5423</issn><eissn>1365-2354</eissn><abstract>Background. To investigate the effectiveness of prehabilitation in improving physical and nutritional status in patients undergoing gastric cancer resection. Methods. A total of 136 locally advanced gastric cancer patients who planned to undergo neoadjuvant chemotherapy (NAC) plus transabdominal radical surgery were involved. All participants were divided into the prehabilitation group and the control group using the odd-even method, with 68 cases in each group. Intervention consisted of preoperative exercise and nutrition optimization. Participants were adults awaiting elective gastric resection for cancer. The primary outcomes were changes in functional ability and nutritional status, as measured by relative changes in 6 minute walking distance (6MWD) and scores on the albumin and prealbumin. Preoperative (end of the prehabilitation period) and postoperative (from 4 to 6 weeks after surgery) data were compared between the two groups. Results. All 136 patients were randomized in this study. Compared with the control group, the prehabilitation group exhibited improved functional capacity both before surgery (6MWD change) and after surgery. Furthermore, it demonstrated significantly higher levels of albumin and prealbumin before and after surgery than the control group. Conclusion. Prehabilitation in gastric cancer patients can improve preoperative functional capacity and nutritional status. Maintaining a patient’s physical function and nutritional status may have a significant impact on the continuity of cancer care.</abstract><cop>Oxford</cop><pub>Hindawi</pub><doi>10.1155/2024/9494994</doi><tpages>9</tpages><orcidid>https://orcid.org/0009-0007-2622-1839</orcidid><orcidid>https://orcid.org/0000-0002-9814-519X</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Abdomen Adjuvant treatment Aerobics Albumin Albumins Angina pectoris Cancer Cancer patients Cancer therapies Care and treatment Chemotherapy Clinical trials Consent Exercise Exercise therapy Fitness training programs Gastric cancer Gastrointestinal surgery Hospitals Intervention Malnutrition Medical prognosis Mortality Nurse practitioners Nutrition Nutritional status Oncology, Experimental Patients Physical fitness Quality of life Recovery (Medical) Rehabilitation Stomach cancer Surgery Tumors |
| title | Clinical Study of Preoperative Prehabilitation Synchronized Neoadjuvant Chemotherapy for Gastric Cancer Patients |
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