Novel and facile process for the preparation of Brexpiprazole an antipsychotic drug

A novel and industrially viable process was developed to synthesize Brexpiprazole an antipsychotic drug. This process involves using 1,4-butanediol as a key starting material, which is then diprotected and subsequently reacted with 7-hydroxy-2(1H)-quinolinone and piperazine-l-benzo[b]thien-4-y1 hydr...

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Veröffentlicht in:Chemical papers 2024-04, Vol.78 (5), p.3017-3022
Hauptverfasser: Satheesh, Deekonda, Reddy, Bhavanam Sekhara, Basavaiah, Keloth, Rao, Vaddi Pandu Ranga, Chavakula, Ramadas, Sreenivasulu, B., Guduri, Anil Kumar
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Sprache:eng
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