A CTL‐Inspired Killing System Using Ultralow‐Dose Chemical‐Drugs to Induce a Pyroptosis‐Mediated Antitumor Immune Function (Adv. Mater. 13/2024)

A CTL‐Inspired Killing System Using Ultralow‐Dose Chemical‐Drugs to Induce a Pyroptosis‐Mediated Antitumor Immune Function (Adv. Mater. 13/2024)

Antitumor Immunotherapy In article 2309839, Qinyang Wang and co‐workers have developed a CTL‐inspired system that mimics the process of T‐cells attacking tumour cells. The system delivers chemotherapeutic drugs to cancer cells under the control of NIR light. The researchers found that this killing s...

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Veröffentlicht in:Advanced materials (Weinheim) 2024-03, Vol.36 (13), p.n/a
Hauptverfasser: Yin, Hao, Xie, Congying, Zuo, Zhigui, Xie, Danli, Wang, Qinyang
Format: Artikel
Sprache:eng
Schlagworte:
antitumor immunotherapy
bioinspired killing system
Drugs
pyroptosis
ultralow‐dose drugs
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Zusammenfassung:Antitumor Immunotherapy In article 2309839, Qinyang Wang and co‐workers have developed a CTL‐inspired system that mimics the process of T‐cells attacking tumour cells. The system delivers chemotherapeutic drugs to cancer cells under the control of NIR light. The researchers found that this killing system enables an ultra‐low dose of chemotherapeutic drugs to trigger pyroptosis‐mediated anti‐tumour immune function, leading to tumour regression.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.202470095