An Enzyme‐Cleavable Solubilizing‐Tag Facilitates the Chemical Synthesis of Mirror‐Image Proteins

Mirror‐image proteins (D‐proteins) are useful in biomedical research for purposes such as mirror‐image screening for D‐peptide drug discovery, but the chemical synthesis of many D‐proteins is often low yielding due to the poor solubility or aggregation of their constituent peptide segments. Here, we...

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Veröffentlicht in:Angewandte Chemie 2024-04, Vol.136 (14), p.n/a
Hauptverfasser: Zheng, Yupeng, Zhang, Baochang, Shi, Wei‐Wei, Deng, Xiangyu, Wang, Tong‐Yue, Han, Dongyang, Ren, Yuxiang, Yang, Ziyi, Zhou, Yong‐Kang, Kuang, Jian, Wang, Zhi‐Wen, Tang, Shan, Zheng, Ji‐Shen
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Sprache:eng
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