Anti-infection effects of heparin on SARS-CoV-2 in a diabetic mouse model

Severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) infection can result in more severe syndromes and poorer outcomes in patients with diabetes and obesity. However, the precise mechanisms responsible for the combined impact of coronavirus disease 2019 (COVID-19) and diabetes have not yet be...

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Veröffentlicht in:	Dōngwùxué yánjiū 2023-11, Vol.44 (6), p.1003-1014
Hauptverfasser:	Zhang, Zhongyun, Zhang, Ning, Lu, Xuancheng, Zhou, Min, Van, Xiaoxiang, Gu, Weiqiong, Yang, Jingru, Zhang, Qin, Zhang, Cheng, Gong, Yuhuan, Jia, Mingjun, Zhang, Xiaoyu, Ning, Peng, Liu, Mei, Li, Xiaoyan, Shi, Xiaomeng, Liu, Wenjun, Gao, George F, Ning, Guang, Wang, Jiqiu, Bi, Yuhai
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Anticoagulants Apoptosis Coronaviruses COVID-19 Cytokeratin Cytokines Diabetes Diabetes mellitus Diet Females Health services Heparin High fat diet Histopathology Hypoxia Hypoxia-inducible factor 1 Hypoxia-inducible factor 1a Infections Inflammation Insulin Lungs Medical research Molecular weight Obesity Pathogenesis Proteins Receptors Respiratory diseases Serum Severe acute respiratory syndrome coronavirus 2 Symptoms Tissue Tissue culture Transgenic animals Transgenic mice Viral diseases
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