Regulation of circGOLPH3 and its binding protein CBX7 on the proliferation and apoptosis of prostate cancer cells

To clarify the mechanism of circGOLPH3 regulation on prostate cancer cells, we performed an overexpression and interference circGOLPH3 assay in prostate cancer cells PC-3 and then evaluated cellular viability, proliferation, cell cycle, and apoptosis of prostate cancer cells by MTT, CCK8, Edu stain,...

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Veröffentlicht in:	Bioscience reports 2020-12, Vol.40 (12), Article 20200936
Hauptverfasser:	Gong, Lifeng, Tang, Yu, Jiang, Li, Tang, Wei, Luo, Shengjun
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biochemistry & Molecular Biology Cancer Cell Biology Cell cycle Cell Cycle, Growth & Proliferation Cell Proliferation Cell viability Flow cytometry Functional testing Gene Expression & Regulation Gene Expression Regulation, Neoplastic Humans Immunoprecipitation Life Sciences & Biomedicine Male Mass spectrometry Mass spectroscopy PC-3 Cells Polycomb Repressive Complex 1 - genetics Polycomb Repressive Complex 1 - metabolism Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Protein Binding Proteins RNA, Circular - genetics RNA, Circular - metabolism RNA-binding protein Science & Technology
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