Chiral Quaternary Ammonium Salt‐Catalyzed Enantioselective Addition Reactions of Hydantoins

We herein report a protocol for the asymmetric 1,4‐addition of hydantoins to various Michael acceptors by utilizing Cinchona alkaloid‐based chiral quaternary ammonium salt catalysts. Various products were obtained with moderate to good enantioselectivities and accompanying computational investigatio...

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Veröffentlicht in:	Helvetica chimica acta 2024-03, Vol.107 (3), p.n/a
Hauptverfasser:	Röser, Katharina, Prameshuber, Lucas, Jahangir, Sajid, Chandra Mallojjala, Sharath, Hirschi, Jennifer S., Waser, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids Ammonium Ammonium Salt Catalysis Ammonium salts Catalysts Chemical reactions DFT Calculations Enantiomers Hydantoin Hydantoins Hydrogen bonding Michael Additions Quaternary ammonium salts
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