Enantioselective Synthesis of Indole‐Derivated Axially Chiral Frameworks via CpXRh(III)‐Catalyzed Domino Cyclization/C3‐Arylation of 2‐Alkynylanilines with 1‐Diazonaphthoquinones

We report herein a chiral CpXRh(III)‐catalyzed domino cyclization/C3‐arylation process using 2‐alkynylanilines and 1‐diazonaphthoquinones as viable substrates, delivering indole‐based derivatives endowed with axial chirality. The method features high enantioselectivity, broad substrate scope, and ro...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Advanced synthesis & catalysis 2024-03, Vol.366 (5), p.1064-1069
Hauptverfasser:	Ye, Junwei, Song, Qingwei, Pan, Dongping, Zeng, Zhongyi, Gao, Hui, Xu, Huiying, Yi, Wei, Zhou, Zhi
Format:	Artikel
Sprache:	eng
Schlagworte:	1-diazonaphthoquinones 2-alkynylanilines Chirality Enantiomers enantioselective synthesis Functional groups indole-derived backbone Rh(III) catalysis Substrates
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!